Results 101 to 110 of about 4,870,076 (306)
Function of MYCT1-TV and MYCT1 in Hep2 and HEK293 cells.
The proliferation of Hep2 and HEK293 cells. B. The apoptosis of Hep2 and HEK293 cells. C. The invasive ability of Hep2 and HEK293 cells. Blank, control cells before transfection; GFP, control cells after transfection with GFP only; MYCT1-TV, cells ...
Wei-Neng Fu (342688) +7 more
core +1 more source
Remimazolam-induced intracellular calcium elevation in HEK293 cells.
(A) Remimazolam at a concentration greater than or equal to 300 μM significantly induced the elevation of intracellular calcium in a dose-dependent manner in HEK293 cells. (n = 3–5, * p (TIF)
Soma Noguchi (12029730) +8 more
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Huntington’s disease modeling on HEK293 cell line
Huntington’s disease is a hereditary neurodegenerative disorder caused by CAG trinucleotide repeat expansion in the first exon of HTT gene. The mutant HTT protein has an elongated polyglutamine tract and forms aggregates in the nuclei and cytoplasm of the striatal neurons. The pathological processes occurring in the medium spiny neurons of Huntington’s
D. V. Sharipova +2 more
openaire +2 more sources
[Mg2+]i values for cells successively incubated for 20 min in solutions containing 10 mM Mg2+ (loading conditions) and for 10 min in completely Mg-free media (efflux conditions) are given. Data are presented as means ± SE.
Gerhard Sponder (446544) +6 more
core +1 more source
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang +12 more
wiley +1 more source
Recognition of agrin from transfected HEK293 cells by agrin+ serum.
Agrin positive serum 2–17 stained positively with HEK293 cells transfected with Flag-agrin construct, co-staining with anti-Flag antibody. Normal human serum cannot recognize agrin-transfected cells.
Beverly Bealmear (85809) +7 more
core +1 more source
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang +11 more
wiley +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Reaction of BG-800 with HEK293 cells expressing SNAPf-ADRβ2 protein.
HEK293 was transiently transfected with SNAPf-ADRβ2 expression plasmid. After 2 d of culture, cells were reacted with BG-800. The fluorescence signal on the cells was measured by scanning on Odyssey Infrared Imaging System.
Aihua Zhang (174376) +8 more
core +1 more source

