Results 81 to 90 of about 150,776 (304)
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Journal of Mazandaran University of Medical Sciences, 2017 Background and purpose: Endothelial growth factor type b with anti-angiogenic activity and inhibition of tumor growth are considered as new anticancer drugs.
Morteza Sadeghi, Zohreh Hojati
doaj
M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells. [PDF]
PLoS ONE, 2013 HEK293 cells have been used extensively to generate stable cell lines to study G protein-coupled receptors, such as muscarinic acetylcholine receptors (mAChRs).
E Scott Graham +6 more
doaj +1 more source
Deciphering µ‐opioid receptor phosphorylation and dephosphorylation in HEK293 cells [PDF]
British Journal of Pharmacology, 2012 BACKGROUND AND PURPOSEThe molecular basis of agonist‐selective signalling at the µ‐opioid receptor is poorly understood. We have recently shown that full agonists such as [D‐Ala2‐MePhe4‐Gly‐ol]enkephalin (DAMGO) stimulate the phosphorylation of a number of carboxyl‐terminal phosphate acceptor sites including threonine 370 (Thr370) and serine 375 ...
Christian, Doll +5 more
openaire +2 more sources
Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability
Advanced Materials Technologies, EarlyView.ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann +9 more
wiley +1 more source
Nicotinic acetylcholine receptor (CHRN) expression and function in cultured human adult fungiform (HBO) taste cells. [PDF]
PLoS ONE, 2018 In rodents, CHRNs are involved in bitter taste transduction of nicotine and ethanol. Currently, it is not clear if CHRNs are expressed in human taste cells and if they play a role in transducing the bitter taste of nicotine and ethanol or in the ...
Jie Qian +6 more
doaj +1 more source
Inducibility & overexpression studies of antiquitin in HEK293 and HepG2 cells [PDF]
, 2005 Wong Wei-yan.Thesis (M.Phil.)--Chinese University of Hong Kong, 2005.Includes bibliographical references (leaves 221-242).Abstracts in English and Chinese.Thesis committee --- p.iDeclaration --- p.iiAcknowledgements --- p.iiiAbstract in Chinese --- p.
core
L35Ae interaction with HEK293 cells
, 2015 HEK293 cells were incubated with 6xHis-tagged L35Ae or anti-hCCR7 Fab17 used as a negative control, followed by immunostaining and flow cytometry analysis. FACS buffer contained PBS, 150 mM NaCl, pH 7.0, 1-1.5% calf serum, and 0.01% NaN3. R-Phycoerythrin
Sergei Permyakov (761167) +1 more
core +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
PLoS ONE, 2014 Bisphenol A (BPA) is an environmental endocrine disruptor which has been detected in human bodies. Many studies have implied that BPA exposure is harmful to human health.
Rong Yin +5 more
doaj +1 more source