Results 41 to 50 of about 132,829 (164)
Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line [PDF]
Mediators of Inflammation, 2017 Chronic inflammation is associated with cancer. CXCL8 promotes tumor microenvironment construction through recruiting leukocytes and endothelial progenitor cells that are involved in angiogenesis. It also enhances tumor cell proliferation and migration.
Zhihui Xiao +2 more
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Adhesion of Enteroaggregative E. coli Strains to HEK293 Cells
BIO-PROTOCOL, 2018 Enteroaggregative Escherichia coli (EAEC) is a recognized cause of acute diarrhea among both children and adults worldwide. EAEC strains are characterized by the presence of aggregative adherence fimbriae (AAF), which play a key role in pathogenesis by mediating attachment to the intestinal mucosa and by triggering host inflammatory responses.
Jorge Ayala-Lujan, Fernando Ruiz-Perez
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Neural Regeneration Research, 2019 Curcumin exerts a neuroprotective effect on Alzheimer’s disease; however, it is not known whether microRNAs are involved in this protective effect. This study was conducted using swAPP695-HEK293 cells as an Alzheimer’s disease cell model. swAPP695-HEK293
Hong-Ying Liu +6 more
doaj +1 more source
Bio-Protocol, 2021 Recombinant proteins are an essential milestone for a plethora of different applications ranging from pharmaceutical to clinical, and mammalian cell lines are among the currently preferred systems to obtain large amounts of proteins of interest due to ...
Silvia Faravelli +5 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background: Almost all Tityus characterized toxins are from subgenera Atreus and Tityus, there are only a few data about toxins produced by Archaeotityus, an ancient group in Tityus genus. Methods: Tityus (Archaeotityus) mattogrossensis crude venom was
Natiela Beatriz de Oliveira +8 more
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Huntington’s disease modeling on HEK293 cell line
Vavilov Journal of Genetics and Breeding, 2017 Huntington’s disease is a hereditary neurodegenerative disorder caused by CAG trinucleotide repeat expansion in the first exon of HTT gene. The mutant HTT protein has an elongated polyglutamine tract and forms aggregates in the nuclei and cytoplasm of the striatal neurons. The pathological processes occurring in the medium spiny neurons of Huntington’s
D. V. Sharipova +2 more
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Kidney & Blood Pressure Research, 2013 Background: Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney, is required for the suppression of 1,25(OH)2D3-generating 25-hydroxyvitamin D3 1-alpha-hydroxylase (Cyp27b1) by FGF23.
Ioana Alesutan +6 more
doaj +1 more source
Dandelion Root Extract Induces Intracellular Ca2+ Increases in HEK293 Cells [PDF]
International Journal of Molecular Sciences, 2018 Dandelion (Taraxacum officinale Weber ex F.H.Wigg.) has been used for centuries as an ethnomedical remedy. Nonetheless, the extensive use of different kinds of dandelion extracts and preparations is based on empirical findings. Some of the tissue-specific effects reported for diverse dandelion extracts may result from their action on intracellular ...
Andrea Gerbino +6 more
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Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor. [PDF]
PLoS ONE, 2012 Despite heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR expression.
Lili Jiang +6 more
doaj +1 more source
Orai1 Expression, Mitosis and Cell Cycle Progression in HEK293 Cells [PDF]
Biophysical Journal, 2010 Calcium influx is needed for cell proliferation and recent identification of Orai1 as the main constituent for both store-operated (SOCE) and non capacitative (NCCE) calcium entries led us to investigate the role of Orai1 in mitosis and cell cycle progression in HEK293 cells.
Borowiec, Anne-Sophie +8 more
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