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Die Innere MedizinHelicobacter pylori was first characterized as an obligate bacterial pathogen in 1983. Since then, substantial advances have been made in understanding the pathophysiology of H. pylori infection, optimizing diagnostic and therapeutic strategies, and expanding testing and treatment-including in the prevention of gastric malignancies.
J. Sarda Carbasse +4 more
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Molecular docking of a set of flavonoid compounds with Helicobacter pylori virulence factors CagA and VacA [PDF]
Journal of HerbMed Pharmacology, 2020 Introduction: Cytotoxin associated gene A (CagA) and vacuolating cytotoxin A (VacA) proteins are the main Helicobacter pylori virulence factors. These toxins are associated with severe gastric diseases.
Mohamed Reda Jouimyi +7 more
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The evolution of SARS-CoV-2 and the COVID-19 pandemic [PDF]
PeerJ, 2023 Scientists have made great efforts to understand the evolution of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) to provide crucial information to public health experts on strategies to control this viral pathogen.
Yuanfang Si +10 more
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Collegian, 1998 H pylori is now recognised as a treatable primary cause of both gastric ulcers and gastric adenocarcinoma. Most infections remain asymptomatic. Persons with signs and symptoms which correlate with potential infection with H pylori should be tested and, if positive, treated with a recognised triple antibiotic regimen.
G, Fisher +3 more
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Journal of Infection in Developing Countries, 2021 Introduction: Helicobacter pylori infection is the major risk factor of atrophic gastritis and intestinal metaplasia. The vacA gene is one of the most virulence factors of H.
Mohamed Reda Jouimyi +9 more
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AORN Journal, 1997 Helicobacter pylori is a gram-negative bacterium which causes chronic gastritis and plays important roles in peptic ulcer disease, gastric carcinoma, and gastric lymphoma. H. pylori has been found in the stomachs of humans in all parts of the world. In developing countries, 70 to 90% of the population carries H. pylori.
B E, Dunn, H, Cohen, M J, Blaser
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Medical Clinics of North America, 2000 H. pylori infection is now recognized as causing serious and life threatening disease in 20% to 30% of those infected. Reliable therapy is problematic. This article addresses the current approach to diagnosis and therapy and new considerations regarding whom to treat. The emphasis of the association of the gastric cancer phenotype of H.
A, Shiotani +3 more
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Armeniaspirol A: a novel anti‐Helicobacter pylori agent
Microbial Biotechnology, 2022 Summary Antibiotic resistance in Helicobacter pylori has been growing worldwide with current treatment regimens. Development of new compounds for treatment of H.
Jia Jia +8 more
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Relationship Between CNVs and Immune Cells Infiltration in Gastric Tumor Microenvironment
Frontiers in Genetics, 2022 Gastric cancer (GC) is a highly fatal and common malignancy of the digestive system. Recent therapeutic advancements have significantly improved the clinical outcomes in GC, but due to the unavailability of suitable molecular targets, a large number of ...
Fazhan Li +17 more
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The impact of dioctyl phthalate exposure on multiple organ systems and gut microbiota in mice
Heliyon, 2023 Dioctyl phthalate, commonly known as bis(2-ethylhexyl) phthalate (DEHP), is a widely used plasticizer in various industries and has been shown to directly or indirectly impact human health. However, there is a lack of comprehensive studies evaluating the
Qiang Zhang +7 more
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