Results 161 to 170 of about 147,687 (343)

Novel Methylation‐Based Model for Accurate Diagnosis of Upper Mediastinal Lymph Node Metastasis in Esophagogastric Junction Adenocarcinoma

open access: yesCancer Science, EarlyView.
DNA methylation‐based diagnostic model enables accurate, noninvasive identification of upper mediastinal lymph node metastasis and may guide personalized treatment strategies for patients with esophagogastric junction adenocarcinoma. ABSTRACT Even after surgical resection, the prognosis is poor for patients with esophagogastric junction adenocarcinoma ...
Yudai Higuchi   +14 more
wiley   +1 more source

Low‐ versus high‐dose azithromycin triple therapy for Helicobacter pylori infection [PDF]

open access: bronze, 1998
Chey   +8 more
openalex   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

open access: yesThe FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro   +2 more
wiley   +1 more source

Clinical features of cardiac nodularity-like appearance induced by Helicobacter pylori infection

open access: hybrid, 2020
Toshihiro Nishizawa   +9 more
openalex   +1 more source

Structural insights for enhanced ROS detoxification of eKatE, a recently identified catalase in atypical E. coli

open access: yesThe FEBS Journal, EarlyView.
We revealed the crystal structure of eKatE from atypical E. coli. eKatE exhibits a hydrogen‐peroxide‐sensitive major channel, a stabilized dimeric interface, an unusual covalent bond between C392 and Y415, and other distinctive features. These structural features contribute to its enhanced catalase activity compared to KatE in typical E.
Eunhee Koh   +7 more
wiley   +1 more source

The OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus

open access: yesHistopathology, EarlyView.
The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.
Pedro Genaro Delgado Guillena   +125 more
wiley   +1 more source

The exposomal imprint on rosacea: More than skin deep

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki   +3 more
wiley   +1 more source

Safety of Potassium‐Competitive Acid Blockers Compared With Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease and Peptic Ulcer Disease: A Systematic Review and Meta‐Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Potassium‐competitive acid blockers (P‐CABs) are a novel class of acid suppressants developed to overcome the limitations of proton pump inhibitors (PPIs), providing rapid and sustained acid suppression. While PPI‐related adverse events (AEs) are well‐documented, safety data on P‐CABs remain limited.
Yewon Jang   +6 more
wiley   +1 more source

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