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The 50 years that have passed since DNA's double-helix structure was elucidated could be commemorated with skills that have evolved from progressive to passe. Pipetting? Prosaic. Gene cloning? Available in off-the-shelf kits. Whole-genome sequencing? Reserved for a handful of high-throughput, highly automated facilities.
openaire +2 more sources
The 3Cat-4 mission aims at demonstrating the capabilities of a CubeSat to perform Earth Observation (EO) by integrating a combined GNSS-R and Microwave Radiometer payload into a 1-Unit CubeSat.
Lara Fernandez +4 more
doaj +1 more source
Improvements in performance of broadband helix traveling-wave tubes. [PDF]
The effectiveness of positive phase velocity tapering to improve the performance of a broadband helix traveling-wave tube (TWT) has been investigated.
Carter, Richard G. +4 more
core +6 more sources
A GAL4-Driver Line Resource for Drosophila Neurobiology
We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer.
Arnim Jenett +35 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Framed Natural Mates of Framed Curves in Euclidean 3-Space
In this study, we consider framed curves as regular or singular space curves with an adapted frame in Euclidean 3-space. We define framed natural mates of a framed curve that are tangent to the generalized principal normal of the framed curve ...
Yanlin Li, Mahmut Mak
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Grip strength has emerged as one of the most robust predictors of mortality, disability and healthspan across populations. Yet its predictive validity rests on an often-unstated assumption: that grip strength serves as a passive readout of systemic ...
Patrick E. Sewell, Christopher Jensen
doaj +1 more source
Biomimetic Membranes as a Technology Platform: Challenges and Opportunities
Biomimetic membranes are attracting increased attention due to the huge potential of using biological functional components and processes as an inspirational basis for technology development.
Claus Hélix-Nielsen
doaj +1 more source
The Society for Vascular Surgery clinical practice guidelines for hemodialysis access, in accordance with the National Kidney Foundation Kidney Disease Outcomes Quality Initiative guidelines and the Fistula First Breakthrough Initiative, recommend consideration of autogenous access over prosthetic conduits whenever possible.
openaire +2 more sources

