Results 41 to 50 of about 452,289 (289)
As part of a multi-state viral genomic surveillance program, we conducted a case-only analysis to evaluate the effectiveness of XBB.1.5-adapated mRNA vaccines in preventing severe illness among individuals with medically attended SARS-CoV-2 infection. We
Matthew E. Levy +23 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. [PDF]
Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data
Judith P Armitage +12 more
core +1 more source
A Modification of the Quad Helix: The “Bi Helix”
The quad helix is well known for its ability to treat posterior crossbites in children with maxillary deficiency. A few authors have also used it for the treatment of unilateral crossbite due to unilateral maxillary deficiency by incorporating modifications in the appliance.
D’souza, Olando K +2 more
openaire +2 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
City of Helix transportation system plan
87 pp. Includes maps and figures. Published June 2001. Received from ODOT January 2, 2007.The Helix Transportation System Plan (TSP) guides the management of existing transportation facilities and the design and implementation of future facilities for ...
Helix (Or.) +2 more
core +1 more source
A GAL4 Driver Resource for Developmental and Behavioral Studies on the Larval CNS of Drosophila
We report the larval CNS expression patterns for 6,650 GAL4 lines based on cis-regulatory regions (CRMs) from the Drosophila genome. Adult CNS expression patterns were previously reported for this collection, thereby providing a unique resource for ...
Hsing-Hsi Li +6 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

