Results 21 to 30 of about 21,210 (213)

Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H., Gething, M. J., Klenk, H. D., Koszinowski, Ulrich H., Waterfield, M. D.   +4 more
core   +2 more sources

Independent and disparate evolution in nature of influenza A virus hemagglutinin and neuraminidase glycoproteins. [PDF]

Proceedings of the National Academy of Sciences, 1990
The hemagglutinin (HA) and neuraminidase (NA) external glycoprotein antigens of H1N1 and H3N2 subtypes of epidemiologically important influenza A viruses prevalent during recent decades were subjected to intensive antigenic analysis by four different methods.
E D, Kilbourne, B E, Johansson, B, Grajower   +2 more
openaire   +2 more sources

Cleavage of hemagglutinin-bearing lentiviral pseudotypes and their use in the study of influenza virus persistence. [PDF]

PLoS ONE, 2014
Influenza A viruses (IAVs) are a major cause of infectious respiratory human diseases and their transmission is dependent upon the environment. However, the role of environmental factors on IAV survival outside the host still raises many questions.
Olivier Sawoo, Amélie Dublineau, Christophe Batéjat, Paul Zhou, Jean-Claude Manuguerra, India Leclercq   +5 more
doaj   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna, Ali, Brown, Bruce, Chen, Enami, Gomez-Puertas, Jeremy Rossman, Johnson, Lai, Leser, Liao, Liu, McCown, McCown, Palese, Pattnaik, Pinto, Rossman, Rossman, Rossman, Rossman, Ruigrok, Schmidt, Takeda, Wang, Wang, Watanabe, Zebedee, Zhang   +29 more
core   +1 more source

A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study

Vaccines, 2018
Influenza viruses cause severe diseases and mortality in humans on an annual basis. The current influenza virus vaccines can confer protection when they are well-matched with the circulating strains.
Raffael Nachbagauer, Florian Krammer, Randy A. Albrecht   +2 more
doaj   +1 more source

Legume Lectins with Different Specificities as Potential Glycan Probes for Pathogenic Enveloped Viruses

Cells, 2022
Pathogenic enveloped viruses are covered with a glycan shield that provides a dual function: the glycan structures contribute to virus protection as well as host cell recognition.
Annick Barre, Els J. M. Van Damme, Bernard Klonjkowski, Mathias Simplicien, Jan Sudor, Hervé Benoist, Pierre Rougé   +6 more
doaj   +1 more source

Properties of an Antigenic Glycoprotein Isolated from Influenza Virus Hemagglutinin [PDF]

Journal of Virology, 1973
A purified antigen, HABA protein, has been derived from influenza virus concentrates by extraction with denaturing solvents. The protein lacks hemagglutinating activity but binds completely strain-specific, hemagglutination-inhibiting antibodies and induces neutralizing antibodies in experimental animals.
openaire   +2 more sources

A Viable Recombinant Rhabdovirus Lacking Its Glycoprotein Gene and Expressing Influenza Virus Hemagglutinin and Neuraminidase Is a Potent Influenza Vaccine [PDF]

Journal of Virology, 2015
ABSTRACT The emergence of novel influenza viruses that cause devastating human disease is an ongoing threat and serves as an impetus for the continued development of novel approaches to influenza vaccines. Influenza vaccine development has traditionally focused on producing humoral and/or cell-mediated immunity, often against the
Alex B, Ryder, Linda, Buonocore, Leatrice, Vogel, Raffael, Nachbagauer, Florian, Krammer, John K, Rose   +5 more
openaire   +2 more sources

Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities

Virology Journal, 2009
Background Influenza virus infection causes significant morbidity and mortality and has marked social and economic impacts throughout the world. The influenza surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), act cooperatively to support ...
Suzuki Takashi, Takahashi Tadanobu, Hiramatsu Hiroaki, Wilairat Prapon, Sriwilaijaroen Nongluk, Ito Morihiro, Ito Yasuhiko, Tashiro Masato, Suzuki Yasuo   +8 more
doaj   +1 more source

Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype

Microbiology Spectrum, 2022
Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health.
Wei Ran, Jacob Schön, Kevin Ciminski, Julian Kraft, Susanne Kessler, Sophie Euchner, Donata Hoffmann, Anne Pohlmann, Martin Beer, Martin Schwemmle, Sebastian Giese   +10 more
doaj   +1 more source