Results 71 to 80 of about 6,574 (157)

Receptor‐like kinases BIR1 and BIR3 modulate antiviral resistance by different mechanisms

New Phytologist, EarlyView.
Summary BRASSINOSTEROID INSENSITIVE1‐ASSOCIATED RECEPTOR KINASE 1 (BAK1)‐INTERACTING RECEPTOR‐LIKE KINASE (BIR) proteins are negative regulators of cell death and defense against microbes in Arabidopsis thaliana. Here, we demonstrate that the members of the BIR family function as negative regulators of antiviral resistance in Arabidopsis.
Carmen Robinson, Irene Guzmán‐Benito, Ana Rocío Sede, Laura Elvira‐González, Chenlei Hua, Malgorzata Ciska, Thorsten Nürnberger, Manfred Heinlein, César Llave   +8 more
wiley   +1 more source

Effects of HA and NA glycosylation pattern changes on the transmission of avian influenza A(H7N9) virus in guinea pigs [PDF]

, 2016
Avian influenza H7N9 virus has posed a concern of potential human-to-human transmission by resulting in seasonal virus-like human infection cases. To address the issue of sustained human infection with the H7N9 virus, here we investigated the effects of ...
Bae, Joon-Yong, Cho, Woo In, Kim, Jin Il, Kim, Juwon, Kim, Yeong-Su, Ko, Yun Young, Lee, Ilseob, Nam, Misun, Park, Man-Seong, Park, Miso, Park, Sehee, Yoo, Kirim, Yun, Soo-Hyeon   +12 more
core   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy

Transplant Infectious Disease, EarlyView.
ABSTRACT Vaccine adjuvants are essential for enhancing immune responses to vaccines, particularly in immunocompromised populations who typically demonstrate suboptimal responses to standard vaccination. This narrative review evaluates the safety and efficacy of approved and candidate adjuvants in immunocompromised hosts, with emphasis on solid organ ...
Haya Hayek, Lana Hasan, Justin Z. Amarin, Yasmeen Z. Qwaider, Olla Hamdan, Wanderson Rezende, Kevin C. Dee, James D. Chappell, Natasha B. Halasa   +8 more
wiley   +1 more source

Avian influenza viral nucleocapsid and hemagglutinin proteins induce chicken CD8+ memory T lymphocytes

Virology, 2010
The avian influenza viruses (AIVs) can be highly contagious to poultry and a zoonotic threat to humans. Since the memory CD8(+) T lymphocyte responses in chickens to AIV proteins have not been defined, these responses to H5N9 AIV hemagglutinin (HA) and nucleocapsid (NP) proteins were evaluated by ex vivo stimulation with virus infected non-professional
Blanca Lupiani, W. E. Briles, Shailbala Singh, Ellen W. Collisson   +3 more
openaire   +3 more sources

Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]

, 2008
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core   +3 more sources

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch, Camilla Reiter Elbæk, Dominik Priesmann, Rune Busk Damgaard   +3 more
wiley   +1 more source

The analysis of the monoclonal immune response to influenza virus. II. The antigenicity of the viral hemagglutinin. [PDF]

The Journal of experimental medicine, 1976
The antigenicity of the hemagglutinins (HA) of five influenza viruses of the A0 and A1 subtypes has been analyzed by means of monoclonal antibodies of murine origin produced in vitro. Secondary monoclonal anti-HA(PR8) antibodies were able to differentiate 14 antigenic determinants (or groups of determinants) on the HA of five influenza virus strains of
openaire   +3 more sources

Dependence of the energies of fusion on the intermembrane separation: optimal and constrained

, 2007
We calculate the characteristic energies of fusion between planar bilayers as afunction of the distance between them, measured from the hydrophobic/hydrophilic interface of one of the two nearest, cis, leaves to the other.
Lee, J. Y., Schick, M.
core   +1 more source