Results 81 to 90 of about 267,118 (262)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Low Dose of IL‐2 Application for Graft‐Versus‐Host Disease Prophylaxis Following Haploidentical Stem Cell Transplantation

MedComm
Graft‐versus‐host disease (GVHD) are still key obstacles of haploidentical transplantation. Interleukin‐2 (IL‐2) could promote natural killer (NK) cells and T‐regulatory cells (Tregs) cells expansion in vitro and in vivo.
Zheng‐Li Xu, Meng Lv, Xing‐Xing Yu, Yi‐Yang Ding, Ting‐Ting Han, Hai‐Xia Fu, Yuan‐Yuan Zhang, Xiao‐Dong Mo, Yu‐Qian Sun, Lan‐Ping Xu, Xiao‐Hui Zhang, Yu Wang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Laparoscopic splenectomy in patients with hematologic malignancies.

, 1999
BACKGROUND: Although laparoscopic splenectomy (LS) for benign hematologic disease is well accepted, its role in hematologic malignancies is not clearly defined. This study examined the efficacy and feasibility of LS for hematologic malignancies. METHODS:
Berman, R S, Feig, B W, Sweeney, J F, Kumparatana, M, Yahanda, Alan M, MD, FACS, Mansfield, P F, Leroux, B, Hemmila, M R, Porter, G A, Pollock, R E   +9 more
core   +1 more source

CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation

Stem Cell Reports, 2019
Summary: Hematopoietic stem and progenitor cells (HSPCs) depend on regulatory cytokines from the marrow microenvironment. From an unbiased cytokine screen of murine marrow supernatants, we identified C-C motif chemokine ligand 5 (CCL5) as an endothelial ...
Sadhna O. Piryani, Angel Y.F. Kam, Uyen T. Vu, Nelson J. Chao, Phuong L. Doan   +4 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Ribavirin for Chronic Hepatitis Prevention among Patients with Hematologic Malignancies

, 2015
Findings among a cohort of 26 patients who had hematologic malignancies and hepatitis E virus (HEV) infection support that HEV can induce chronic hepatitis.
Huguet, Françoise, Loïc Ysebaert, Françoise Huguet, Christian Recher, Roussel, Murielle, Nassim Kamar, Oberic, Lucie, Alric, Laurent, Faguer, Stanislas, Jean-Marie Peron, Murielle Roussel, Beyne-Rauzy, Odile, Lucie Oberic, Laurent Alric, Suzanne Tavitian, Huynh, Anne, Odile Beyne-Rauzy, Anne Huynh, Stanislas Faguer, Ysebaert, Loïc, Tavitian, Suzanne, Kamar, Nassim, Abravanel, Florence, Recher, Christian, Clément Gaudin, Florence Abravanel, Peron, Jean-Marie, Gaudin, Clément   +27 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Unrelated cord blood transplants in adults with hematologic malignancies

, 2006
We analyzed outcomes and risk factors after unrelated cord blood transplantation (CBT) in adults with hematologic ...
de Lima, M, ARCESE, WILLIAM, Gluckman, E, Sanz, G, Rocha, V, Gluckman, E., Busca, A, Asano, S, Arcese, W, Iori, A, Ionescu, I, Wernet, P, Labopin, M, Sirvent, A   +13 more
core