Results 91 to 100 of about 267,118 (262)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Allergy and risk of hematologic malignancies: Associations and mechanisms

, 2014
Increasing evidence indicates that a dysregulated immune system, as the one found in allergic disorders, can affect survival of tumor cells. A possible association between allergies and risk of hematologic malignancies has been examined in several ...
A. Allegra, P.L. Minciullo, S. Gangemi, C. Musolino, ALLEGRA, Alessandro, MINCIULLO, PAOLA LUCIA, GANGEMI, Sebastiano, MUSOLINO, Caterina   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ambulatory mediastinal biopsy for hematologic malignancies

, 1997
Objective: We retrospectively evaluated our experience with outpatient surgical biopsy of mediastinal lesions in patients with hematologic malignancies, its cost-effectivness and ability to allow diagnosis.
C. Ricci, DE GIACOMO, Tiziano, VENUTA, Federico, RENDINA, Erino Angelo, E. O. Pescarmona, I. Flaishman, E. Guarino, F Venuta   +7 more
core   +1 more source

Unbalanced whole-arm translocation der(1;13) in hematologic malignancies [PDF]

, 2016
Whole-arm chromosome translocations involving the long arm of chromosome 1 are nonrandom aberrations in hematologic malignancies that commonly involve acrocentric chromosomes.
Al Bahar, Soad, Zamecnikova, Adriana
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Review of advances in CAR-T therapies in malignant hematology

Frontiers in Oncology
There have been numerous advancements in immune cell effector therapies in the malignant hematology space. This review article explores the pivotal studies that led to the approval of chimeric antigen receptor T-cell (CAR-T) therapies for hematologic ...
Neda Amirmokhtari, Neda Amirmokhtari, Forat Lutfi, Forat Lutfi   +3 more
doaj   +1 more source

A retrospective study on beta-blocker use and outcomes in hematopoietic stem cell transplant patients [PDF]

PeerJ
Recent studies have linked beta-blocker (BB) use in critical care settings with improved survival outcomes, potentially due to beta-adrenergic receptor (β-AR) blockade and associated anti-inflammatory effects.
Matthew A. Bergens, John T. Bokman, Ernaya J. Johnson, Matthew L. Braun, Yan Li, Amy T. Bush, Lauren Hill, Jolien Van Opstal, Alessandro Racioppi, Rebecca Fan, Sejal Kaushik, Edwin Alyea, Nelson Chao, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Richard Lopez, Sendhilnathan Ramalingam, Keith Sullivan, Paul Wischmeyer, Anthony D. Sung   +20 more
doaj   +2 more sources

Direct Oral Anticoagulants In Patients With Hematologic Malignancies

, 2020
The anticoagulant treatment for patients with hematologic malignancies is low molecular weight heparin (LMWH), considered the safest in this particular patients setting. Although direct oral anticoagulants (DOACs) have proven their efficacy and safety in
Chistolini, Antonio, Maria L. De Luca, Serrao, Alessandra, Santoro, Cristina, Alessandra Serrao, Luciano Fiori, Antonietta Ferretti, Ferretti, Antonietta, De Luca, Giulia, Cristina Santoro, Antonio Chistolini, Ligia, Silvio, Fiori, Luciano, Massimo Breccia, Mohamed, Sara, Gianfranco Lapietra, Sara Mohamed, Lapietra, Gianfranco, De Luca, Maria Lucia, Breccia, Massimo, Giulia De Luca, Silvio Ligia   +21 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source