Hematopoietic Cell Transplantation for Lymphomas
Background The heterogeneity of lymphomas results in numerous treatment options, including both autologous and allogeneic hematopoietic cell transplantation. However, the type of transplantation, the timing the procedure, and the selection of suitable patients for transplant continue to evolve.
Ernesto, Ayala, Marcie, Tomblyn
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APPENDICEAL DISEASE IN HEMATOPOIETIC CELL TRANSPLANTATION [PDF]
Appendiceal diseases are relatively rare reported complications during hematopoietic stem cell transplantation with no guidance on management. Pre- and post-transplant patients should receive a trial of medical therapy with appendectomy after recovery but prior to transplant in the former and plan for appendectomy after completion of immunosuppression ...
Zachary Wright +5 more
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Haploidentical hematopoietic cell transplantation [PDF]
Haploidentical hematopoietic stem cell transplantation (HSCT) provides an opportunity for nearly all patients to benefit from HCT when a HLA genotypically matched sibling is not available. Initial results with the use of mismatched allografts led to limited enthusiasm due to GVHD and infectious complications resulting in unacceptable treatment-related ...
L-P, Koh, N, Chao
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Severe infections and infection-related mortality in a large series of haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide [PDF]
Severe infections and their attributable mortality are major complications in recipients of allogeneic hematopoietic stem cell transplantation (alloSCT). We herein report 236 adult patients who received haploSCT with PTCy.
Martino Bofarull, Rodrigo +36 more
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Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation: a global observational study [PDF]
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro +31 more
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Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas +11 more
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Hematopoietic chimerism after allogeneic stem cell transplantation : a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization [PDF]
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias.
Wachowiak, Jacek +13 more
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The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K. +38 more
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Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma [PDF]
We report the outcomes after reduced-intensity conditioning allogeneic stem cell transplantation (RIT) for non-Hodgkin lymphoma (NHL) in 88 patients (low-grade NHL [LG-NHL], n = 41; high-grade NHL [HG-NHL], n = 37; mantle cell lymphoma [MCL], n = 10 ...
Mahendra, P +37 more
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Arrhythmias in the setting of hematopoietic cell transplants [PDF]
Prior studies report that 9-27% of persons receiving a hematopoietic cell transplant develop arrhythmias, but the effect on outcomes is largely unknown. We reviewed data from 1177 consecutive patients ⩾40 years old receiving a hematopoietic cell transplant at one center during 1999-2009.
Tonorezos, Emily S. +11 more
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