Results 171 to 180 of about 1,162,311 (403)
Advanced Science, EarlyView.This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen +3 more
wiley +1 more source
A study of murine bone marrow cells cultured in bioreactors which create an environment which simulated microgravity [PDF]
Previous research indicated that mouse bone marrow cells could be grown in conditions of simulated microgravity. This environment was created in rotating bioreactor vessels. On three attempts mouse cells were grown successfully in the vessels.
Lawless, Brother Desales
core +1 more source
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
Nature Network Boston, 2015 Jianhui Chang +17 more
semanticscholar +1 more source
Advanced Science, EarlyView.Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen +14 more
wiley +1 more source
Advanced Science, EarlyView.CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong +16 more
wiley +1 more source
Hematopoietic Stem Cells and Hematopoiesis
Cancer Control, 2003 Background The highly orchestrated process of blood cell development and homeostasis is termed “hematopoiesis.” Understanding the biology of hematopoietic stem cells as well as hematopoiesis is important to developing improved treatments for hematologic malignancies, congenital disorders, chemotherapy-related cytopenias, and blood and marrow ...
openaire +2 more sources
Advanced Science, EarlyView.A multianchor transfer learning method, SemiLT, enables accurate cell label annotation in sparse scATAC‐seq data by leveraging well‐annotated scRNA‐seq references. By addressing temporal discrepancies between modalities, SemiLT improves rare cell type identification and batch correction.
Zhitong Chen +3 more
wiley +1 more source
Rates of mutation to growth factor autonomy and tumorigenicity differ in hematopoietic stem and precursor cells expressing the multilineage colony-stimulating factor gene. [PDF]
, 1989 Christine Laker +8 more
openalex +1 more source
Advanced Science, EarlyView.The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang +12 more
wiley +1 more source