Results 181 to 190 of about 211,095 (268)

Harnessing DNA barcoding to enhance and sustain polyclonality in gene-edited hematopoietic stem cells. [PDF]

Mol Ther Methods Clin Dev
Ojeda-Perez I, Bustos A, Selvaraj S, Fañanas-Baquero S, Alberquilla-Fernandez O, Serrano LJ, Bonafont J, Garcia-Torralba A, Torres-Ruiz R, Rodriguez-Perales S, Lang V, Trigueros C, Mayo-Garcia R, Quintana-Bustamante O, Porteus M, Sánchez-Dominguez R, Segovia JC.   +16 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

<i>Mmrn1</i> expression defines a novel subset of hematopoietic stem cells and leukemia stem cells with great self-renewal potential. [PDF]

Haematologica
Chen N, Yang L, Chen F, Zeng H, Zhong X, Liu Y, Chen Z, Yao M, Lu Y, Shen M, Chen M, Xu Y, Wang S, Zhang X, Wang J, Hu M.   +15 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early-life <i>DNMT3A</i> mutations. [PDF]

Hemasphere
Derks LLM, Müskens KF, van Roosmalen MJ, de Graaf AO, Epskamp N, Trabut L, Hagelaar R, Jansen JH, Lindemans CA, van Bergen MGJM, van Boxtel R, Belderbos ME.   +11 more
europepmc   +1 more source

[Hematopoietic stem cell niche].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2012
openaire   +2 more sources

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients. [PDF]

Adv Sci (Weinh)
Lee H, Kim EK, Ju HY, Lee CR, Ahn S, Kim ES, Myung K, Kim WK, Cho SY, Kwon Y, Kim D, Yu Y, Kwon EJ, Kim H, Mun SI, Lim DM, Kim K, Heo HJ, Baek SE, Lee SY, Cho H, Choi EY, Goh TS, Baryawno N, Lee D, Jung KS, Yoo KH, Oh CK, Kim YH.   +28 more
europepmc   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Correction: The dark side of stemness - the role of hematopoietic stem cells in development of blood malignancies. [PDF]

Front Oncol
Filipek-Gorzała J, Kwiecińska P, Szade A, Szade K.   +3 more
europepmc   +1 more source