Results 171 to 180 of about 217,775 (266)

Iron overload damages mitochondria and induces metabolic rewiring of hematopoietic stem cells toward glycolysis.

Blood
Sighinolfi S, Cassina L, Lidonnici MR, Beretta S, Stefanoni D, Storto M, Mayerhofer C, Kristiansen TA, Scadden DT, Merelli I, Boletta A, Aprile A, Ferrari G.   +12 more
europepmc   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Elevated levels of Ube2g1 in hematopoietic stem cells lead to segmental aging of the hematopoietic system. [PDF]

Haematologica
Niemann J, Schuster T, Sakk V, Soller K, Brown A, Wiese S, Eiwen K, Hoenicka M, Liebold A, Oltmanns M, Reichel H, Mulaw MA, Geiger H.   +12 more
europepmc   +1 more source

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source

NCOA2 promotes the return of hematopoietic stem cells to quiescence after irradiation stress by regulating FOXO3a-dependent mitophagy. [PDF]

Hemasphere
Chen F, Chen N, Wang L, Zeng H, Lu Y, Liu Y, Chen J, Xu Y, Chen M, Wang S, Shen M, Wang J, Hu M.   +12 more
europepmc   +1 more source

Bone marrow‐like viscosity affects imatinib resistance in chronic myeloid leukemia

Biotechnology Progress, EarlyView.
Physical cues such as microenvironmental viscosity have been recognized as important regulators in controlling cell functions. However, even though the bone marrow (BM) is a viscous tissue in which cells respond mechanically to both the matrix stiffness and the viscosity of surrounding fluid, the impact of microenvironmental viscosity on imatinib (IM ...
Tianjiao Zeng, Huajian Chen, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +6 more
wiley   +1 more source

Correction: Efficacy and safety of camrelizumab plus apatinib for solid tumors: a meta-analysis

Frontiers in Immunology
Ping Yu, Xiaoyu Song, Xiaoyu Song, Yue Li, Xuanlong Chen, Xuanlong Chen, Yuan Zhou, Yuan Zhou, Fei Jiang   +8 more
doaj   +1 more source

NO-immune privilege for hematopoietic stem cells. [PDF]

Cell Res
Chédeville AL, Méndez-Ferrer S.
europepmc   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Insights and modulation of RNA polymerase-dependent R-loop and dsRNA in Fanconi anemia hematopoietic stem cells. [PDF]

JCI Insight
Hashimoto M, Feng X, Bai J, Zeng H, Li T, Li J, Umemoto T, Andreassen PR, Huang G.   +8 more
europepmc   +1 more source