EGFR-dependent endocytosis of Wnt9a and Fzd9b promotes β-catenin signaling during hematopoietic stem cell development in zebrafish [PDF]
Nicole Nguyen +8 more
openalex +1 more source
880. Hematopoietic Stem Cell Gene Therapy for the Treatment of Metachromatic Leukodystrophy: Clinical Trial Design [PDF]
openalex +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Erratum: Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells. [PDF]
Shi Z +10 more
europepmc +1 more source
Minimal Change Nephrotic Syndrome after Allogenic Hematopoietic Stem Cell Transplantation
Yuji Sato +5 more
openalex +2 more sources
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
The impact of dietary restriction on transcriptional profiles of hematopoietic stem cells in aged female mice. [PDF]
Yu C +7 more
europepmc +1 more source
Targeting the Spleen as an Alternative Site for Hematopoiesis [PDF]
Lim, Hong +3 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source

