Results 71 to 80 of about 211,095 (268)
Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells
Haematologica, 2012 Background Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell ...
Fabio Di Giacomo +6 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice
Haematologica, 2020 Sarah Ebinger +12 more
doaj +1 more source
Journal of Lipid ResearchLiver injury is closely related to poor outcomes in sepsis patients. Current studies indicate that sepsis is accompanied by metabolic disorders, especially those related to lipid metabolism.
Ying Feng +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Haematologica, 2011 Background Human bone marrow and umbilical cord blood are sources of allogeneic hematopoietic stem cells for transplantation, which is a life-saving treatment in a variety of diseases but is burdened by delayed T-cell reconstitution.
Magda De Smedt +5 more
doaj +1 more source
Hematopoietic stem cell mobilization
Haematologica, 2008 Recruitment of hematopoietic stem/progenitor cells (HSC) from the bone marrow into peripheral blood following treatment with chemotherapy and/or cytokines is termed mobilization. The release of HSC from the bone marrow is a physiological phenomenon for the protection of HSC from toxic injury ...
LEMOLI, ROBERTO MASSIMO, D'Addio A.
openaire +4 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source