Results 151 to 160 of about 153,280 (319)
The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling
ChemBioChem, EarlyView.Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch +3 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 168-180, January 2023., 2023 The hydro‐ethanolic extract of P. granatum peel was standardized. ;The extract increased superoxide dismutase activity and thiol content, while reduced function of AchE and peroxidation of lipid in the scopolamine‐injured rat’s brain. ;P. granatum may attenuate scopolamine injury through targeting nuclear factor‐E2‐related factor 2 pathway ; Abstract ...
Mahsan Akbarian +5 more
wiley +1 more source
Boron‐Based Functionalities Enhance, the Potency of 2,5‐Dimethylfuran‐Based IDO1 Inhibitors
ChemBioChem, EarlyView.‐, , , ‐ , Indoleamine‐2,3‐dioxygenase‐1 (IDO1), a key immunoregulatory enzyme, is inhibited by novel boron derivatives (closo‐1,2‐ and 1,7‐carborane, boronic acids and esters, and benzoxaboroles) of 2,5‐dimethylfuran, each displaying low μM affinity for the human recombinant enzyme.
Thomas J. C. Carraro +4 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 249-260, January 2023., 2023 This study indicated, for the first time, that (±) linalool and its enantiomer, (R)‐(‐) linalool protected PC12 cells against injury induced by oxygen and glucose deprivation/reoxygenation (OGD/R) via the mitigation of oxidative stress and the downregulation of Bax/Bcl‐2, caspase‐3 and caspase‐9, resulting in decreased apoptotic cell death.
Azar Hosseini +5 more
wiley +1 more source
The heme-heme oxygenase system in inflammation [PDF]
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openaire +1 more source
ChemBioChem, Accepted Article.Heme‐containing unspecific peroxygenases (UPOs) have catched significant attention as biocatalysts for oxidation reactions due to their ability to function without expensive nicotinamide cofactors. In our recent study, the UPO from Aspergillus brasiliensis (AbrUPO) was found to catalyze the aromatic hydroxylation of substituted benzenes, a feature that
Fabian Schmitz +8 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 295-306, January 2023., 2023 An excess of reactive oxygen species (ROS) can cause cell damage, and an accumulation of damage leads to cellular dysfunction resulting in a variety of diseases including abnormal aging, cancer, diabetes, and inflammation. In this study, feruloyl oligosaccharides (FOs) were obtained by solid‐state fermentation using wheat bran, and antioxidant activity
Qiuyan Chen +8 more
wiley +1 more source
ChemCatChem, EarlyView.A study of crystallographic complexes obtained from vanadium haloperoxidase enzymes can determine key amino acids, leucine, and phenylalanine, that change their structural orientation to allow either chloride or bromide to bind to the enzymes active site, thereby determining halide specificity.
Daniel E. Mitchell +3 more
wiley +1 more source