Results 161 to 170 of about 339,218 (339)
Advanced Science, EarlyView.Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang +12 more
wiley +1 more source
Advanced Science, EarlyView.Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma +5 more
wiley +1 more source
A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease
Advanced Science, EarlyView.DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu +9 more
wiley +1 more source
Investigations of the Role of Iron in Chlorophyll Metabolism I. Effect of Iron Deficiency on Chlorophyll and Heme Content and on the Activities of Certain Enzymes in Leaves [PDF]
, 1963 H. V. Marsh, Harold J. Evans, G. Matrone
openalex +1 more source
The heme-heme oxygenase system in inflammation [PDF]
, 2002 Item does not contain ...
openaire +1 more source
Biomolecular Interaction Prediction: The Era of AI
Advanced Science, EarlyView.This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley +1 more source
Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
Angewandte Chemie, EarlyView.In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun +9 more
wiley +2 more sources
Bacteriochlorophyll and Heme Synthesis in Rhodopseudomonas spheroides : Possible Role of Heme in Regulation of the Branched Biosynthetic Pathway [PDF]
, 1969 June Lascelles, T P Hatch
openalex +1 more source