Results 201 to 210 of about 73,522 (298)

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia. [PDF]

open access: yesFront Mol Neurosci
Zou XY   +8 more
europepmc   +1 more source

Occupational Exposure to Factory‐Derived Particulate Matter 2.5 Induces Cutaneous Toxicity in Workers and HaCaT Keratinocytes Through Oxidative Stress and Inflammation

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 2145-2157, June 2026.
ABSTRACT This study aimed to evaluate the toxicological effects of occupational exposure to factory‐derived particulate matter (PM2.5) on human skin, emphasizing its role as a potential target organ of environmental toxicants. An epidemiological survey comparing factory and nonfactory workers was conducted by assessing their skin elasticity and color ...
Miku Tanaka   +7 more
wiley   +1 more source

Mitigation of Cisplatin‐Induced Neurotoxicity via Nrf2/HO‐1 Signaling and Autophagy: The Protective Role of Vitamin D

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study investigates the neuroprotective effect of vitamin D against cisplatin‐induced mitochondrial damage and oxidative stress (ROS). HO‐1 expression is increased by vitamin D, which triggers Nrf2 activation and nuclear translocation. The results demonstrate that vitamin D protects brain tissue by strengthening the antioxidant defense system ...
Songul Cuglan   +2 more
wiley   +1 more source

Heme Oxygenase-1 Expression as a Prognostic Marker in Early-Stage HCC Undergoing Resection or Liver Transplantation. [PDF]

open access: yesLife (Basel)
Cadar R   +12 more
europepmc   +1 more source

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza   +8 more
wiley   +1 more source

PFAS properties and destruction methods: A focus on enzymatic degradation

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1126-1152, June 2026.
Abstract Per‐ and polyfluoroalkyl substances (PFAS) are known as ‘forever’ chemicals and have lasting detrimental impact on the environment and living organisms. To understand PFAS molecules better, this review begins with an overview of PFAS definition, classifications and applications, and then provides a comprehensive summary and critical analysis ...
Guobin Liang, Hua Zhao
wiley   +1 more source

Biogenic Silver Nanoparticles in Diabetes: In Vivo Mechanisms, Therapeutic Potential, and Future Perspectives: A Review

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Biogenic silver nanoparticles exhibit antidiabetic potential by improving glycemic control, enhancing insulin sensitivity, and preserving pancreatic β‐cell function. They act through antioxidant and anti‐inflammatory mechanisms, modulating ROS, NF‐κB, and PI3K/Akt pathways, while providing multi‐organ protection, highlighting their promise as ...
Nourhane A. Darwich   +2 more
wiley   +1 more source

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