Results 271 to 280 of about 137,322 (324)

Reduction in Renal Heme Oxygenase-1 Is Associated with an Aggravation of Kidney Injury in Shiga Toxin-Induced Murine Hemolytic-Uremic Syndrome. [PDF]

Toxins (Basel)
Mestekemper AN, Pirschel W, Krieg N, Paulmann MK, Daniel C, Amann K, Coldewey SM.   +6 more
europepmc   +1 more source

Peripheral human red blood cell development in human immune system mouse model with heme oxygenase-1 deficiency. [PDF]

Blood Adv
Patel AK, Trageser K, Kim H, Lim W, Adler C, Porter B, Ni M, Wei Y, Atwal GS, Bigdelou P, Kulshreshtha V, Ajithdoss D, Zhong J, Tu N, Macdonald L, Murphy A, Frleta D.   +16 more
europepmc   +1 more source

Mechanism by which hydrogen-rich water mitigates exercise-induced fatigue: activation of the immunoresponsive gene 1-itaconate/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway. [PDF]

Med Gas Res
Zhang Y, Ying Y, Zu X, Ding L, Shi X, Wang J, Li X, Li C, Zhou Q, Shen H, Li H, Lu H, Cheng J.   +12 more
europepmc   +1 more source

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Heme-Oxygenase-1

Antioxidants & Redox Signaling, 2020
This Forum issue “Heme Oxygenase” (HO) includes original research articles and reviews that are aimed at understanding the role of HO-1 in several pathophysiological conditions, specially addressing those involving inflammation and oxidative damage ...
Mara Facchinetti
semanticscholar   +6 more sources

Heme Oxygenase-1

American Journal of Respiratory Cell and Molecular Biology, 2002
Oxidative stresses such as oxidant stimuli, inflammation, exposure to xenobiotics, and ionizing irradiation elicit various tissue injuries and provoke cellular responses, principally involving transcriptional activation of genes encoding proteins which participate in the defense reactions (Camhi et al., 1995).
Toru Takahashi, Reiko Akagi, Hiroko Shimizu, Masahisa Hirakawa, Shigeru Sassa   +4 more
openaire   +3 more sources

Heme Oxygenase-1

American Journal of Respiratory and Critical Care Medicine, 2005
As aspects of basic science come to play an increasingly prominent role in clinical medicine, heme oxygenase-1 is one of several molecules emerging as a central player in diseases of the lung and intensive care unit. Although the apparent raison d'être of this enzyme is to dispose of heme, its activity results in cytoprotection against oxidative injury
Danielle, Morse, Augustine M K, Choi
openaire   +3 more sources

Inducers of Heme Oxygenase-1

Current Pharmaceutical Design, 2008
Heme oxygenase-1 (HO-1) is an inducible rate-limiting enzyme which catalyzes group heme into carbon monoxide, iron and bilirubin. In the recent years, HO-1 expression has been reported as an important protective endogenous mechanism against physical, chemical and biological stress.
FERRÁNDIZ, M.L., Devesa Giner, Isabel
openaire   +3 more sources

Pharmacologic Induction of Heme Oxygenase-1

Antioxidants & Redox Signaling, 2007
Heme oxygenase-1 (HO-1) is a cytoprotective protein whose expression is consistently associated with therapeutic benefits in a number of pathologic conditions such as atherosclerotic vascular disease and inflammation. Although the expression of HO-1 in most tissues is low, a large number of clinical and experimental pharmacologic compounds have been ...
Cheng, Li, Parastu, Hossieny, Ben J, Wu, Abdelqader, Qawasmeh, Konstanze, Beck, Roland, Stocker   +5 more
openaire   +2 more sources

Heme oxygenase-1 and chronic hypoxia

Respiratory Physiology & Neurobiology, 2012
A myriad of changes are necessary to adapt to chronic hypoxemia. Key among these changes increases in arterial oxygen carrying capacity, ventilation and sympathetic activity. This requires the induction of several gene products many of which are regulated by the activity of HIF-1α, including HO-1.
Judith A, Neubauer, Jag, Sunderram
openaire   +2 more sources

Heme oxygenase-1 in organ transplantation

Frontiers in Bioscience, 2007
Cells have a plethora of defense mechanisms that are activated upon exposure to oxidative stress. These aim at limiting the deleterious effects of oxidative stress and re-establishing homeostasis. In the particular context of organ transplantation, these defense mechanisms contribute to sustain graft survival via at least two interrelated mechanisms ...
Miguel P, Soares, Fritz H, Bach
openaire   +2 more sources