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Correction: Atorvastatin inhibits Lipopolysaccharide (LPS)-induced vascular inflammation to protect endothelium by inducing Heme Oxygenase-1 (HO-1) expression. [PDF]

PLoS One
Luo J, Zhu Q, Huang K, Wen X, Peng Y, Wei G, Chen G.   +6 more
europepmc   +1 more source

Heme oxygenase-1 modulates CD62E-dependent endothelial cell-monocyte interactions and mitigates HLA-I-induced transplant vasculopathy in mice. [PDF]

Front Immunol
Schuster L, Zaradzki M, Janssen H, Gallenstein N, Etheredge M, Hofmann I, Weigand MA, Immenschuh S, Larmann J.   +8 more
europepmc   +1 more source

Heme Oxygenase-1 and Prostate Cancer: Function, Regulation, and Implication in Cancer Therapy. [PDF]

Int J Mol Sci
Salloom RJ, Ahmad IM, Sahtout DZ, Baine MJ, Abdalla MY.   +4 more
europepmc   +1 more source

The anti-cancer role of tumor protein p53-inducible nuclear protein 2/nuclear factor-kB/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway in spinal cord glioma. [PDF]

Cytojournal
Huang J, Pan Z, Yu L, Zhu X, Wang Y, Zhou Y, Huang K, Zhu X.   +7 more
europepmc   +1 more source

Immunoregulatory Properties of Heme Oxygenase-1

, 2010
Heme oxygenase-1 (HO-1) is one of the three isoforms of the heme oxygenase enzyme that catabolyzes the degradation of heme into biliverdin with the production of free iron and CO. HO-1 is induced by its substrate and by other stimuli, including agents involved in oxidative stress and proinflammatory cytokines as well as several anti-inflammatory ...
Blancou, Philippe, Tardif, Virginie, Simon, Thomas, Rémy, Séverine, Carreño, Leandro, Kalergis, Alexis M., Anegon, Ignacio   +6 more
openaire   +4 more sources

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Heme-Oxygenase-1

Antioxidants & Redox Signaling, 2020
This Forum issue “Heme Oxygenase” (HO) includes original research articles and reviews that are aimed at understanding the role of HO-1 in several pathophysiological conditions, specially addressing those involving inflammation and oxidative damage.
openaire   +4 more sources

Heme Oxygenase-1

American Journal of Respiratory and Critical Care Medicine, 2002
Oxidative stresses such as oxidant stimuli, inflammation, exposure to xenobiotics, and ionizing irradiation elicit various tissue injuries and provoke cellular responses, principally involving transcriptional activation of genes encoding proteins which participate in the defense reactions (Camhi et al., 1995).
Toru Takahashi, Reiko Akagi, Hiroko Shimizu, Masahisa Hirakawa, Shigeru Sassa   +4 more
openaire   +2 more sources

Inducers of Heme Oxygenase-1

Current Pharmaceutical Design, 2008
Heme oxygenase-1 (HO-1) is an inducible rate-limiting enzyme which catalyzes group heme into carbon monoxide, iron and bilirubin. In the recent years, HO-1 expression has been reported as an important protective endogenous mechanism against physical, chemical and biological stress.
FERRÁNDIZ, M.L., Devesa Giner, Isabel
openaire   +3 more sources

Heme Oxygenase-1 in Lung Disease

Current Drug Targets, 2010
The lungs are a major target for various inflammatory, oxidative, carcinogenic or infectious stressors, which result in a range of lung diseases. Induction of heme oxygenase-1 (HO-1) during acute and chronic lung processes is a crucial defense mechanism.
Chintan M, Raval, Patty J, Lee
openaire   +2 more sources