Results 111 to 120 of about 133,631 (206)

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

Molecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti, Martina Giuseffi, Eugenia Giglio, Graziella Marino, Marisabel Mecca   +4 more
wiley   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

Neuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos. [PDF]

J Histochem Cytochem, 2023
Rana M, Bajaj D, Choubey P, Jain S, Basu-Modak S.   +4 more
europepmc   +1 more source

Quality Control of Shenqi Tongmai Oral Liquid Based on Quantitative Analysis of Multicomponents by Single Marker, Molecular Docking, and Multivariate Statistics

Phytochemical Analysis, EarlyView.
ABSTRACT Introduction Shenqi Tongmai oral liquid (SQTM) is famous for its remarkable effect in the treatment of cardiovascular diseases. However, the SQTM quality evaluation system has not been established. Objective The objective of this study is to establish a method for the determination of nine components of SQTM and to screen quality control ...
Qian Li, Li Wang, Liuping Tan, Xiaojing Tao, Bei Zhang, Jingnan Pei, Qiuping Li   +6 more
wiley   +1 more source

Plasticity of Gene Expression in Spaceflight and Postflight in Relation to Cardiovascular Disease: Mechanisms and Candidate Repurposed Drugs

PROTEOMICS, EarlyView.
ABSTRACT Spaceflight poses unique challenges to human health due to exposure to increased levels of cosmic radiation, microgravity, and associated oxidative stress. These environmental factors can lead to cellular damage, inflammation, and a range of health complications, including cardiovascular problems, immune system impairment, and an increased ...
Marilena M. Bourdakou, Eleni M. Loizidou, George M. Spyrou   +2 more
wiley   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

Structural Engineering of Sonosensitive Nanohybrids by Active Vanadium Species toward Collapse of Multi‐Antioxidant Defenses and Boosted Therapy of Triple‐Negative Breast Cancer

Small Structures, EarlyView.
A sonosensitive nanohybrid with defect structures is constructed through in situ etching deposition of vanadyl phosphate onto porphyrin metal–organic frameworks (MOFs), in which defects induce narrower bandgap and serve as charge traps for enhancing singlet oxygen generation under ultrasound irradiation. Additionally, released vanadium species overcome
Tingting Zhang, Jing Zhu, Yunyun Wu, Daqing Xia, Xiyue Xie, Lin Li, Zhenqiang Wang, Kaiyong Cai, Jixi Zhang   +8 more
wiley   +1 more source

The macrophage heme-heme oxygenase-1 system and its role in inflammation.

Biochemical Pharmacology, 2018
Vijith Vijayan, F. Wagener, S. Immenschuh   +2 more
semanticscholar   +1 more source

Heme oxygenase/carbon monoxide system affects the placenta and preeclampsia. [PDF]

Med Gas Res
Mahan VL.
europepmc   +1 more source