Results 151 to 160 of about 60,693 (303)

Overexpression of Heme Oxygenase-1 in Mesenchymal Stem Cells Augments Their Protection on Retinal Cells In Vitro and Attenuates Retinal Ischemia/Reperfusion Injury In Vivo against Oxidative Stress [PDF]

, 2017
Li Li, Gaiping Du, Dajiang Wang, Jin Zhou, Guomin Jiang, Hua Jiang   +5 more
openalex   +1 more source

Cryo‐EM reveals an ensemble of cytochrome P450 reductase conformations in solution

Protein Science, Volume 35, Issue 2, February 2026.
Abstract The eukaryotic electron transport system, mediated by cytochrome P450 reductase (CPR), plays a crucial role in driving myriads of reactions involved in the biosynthesis of physiologically active compounds (such as sterols, steroids, vitamins, and natural products), as well as in the metabolism of drugs, toxins, and carcinogens.
Galina I. Lepesheva, Tatiana Y. Hargrove, Yi Ren   +2 more
wiley   +1 more source

A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
An iron‐based, enzyme‐triggered CO‐releasing molecule (ET‐CORM) is site‐specifically conjugated to the antibody trastuzumab. This novel ET‐CORM‐antibody conjugate releases carbon monoxide upon cleavage by the tumor‐associated protease cathepsin B. The construct enables selective intracellular CO delivery to HER2‐overexpressing and CatB‐expressing cells,
Inga Černauskienė, Eduardo Izquierdo‐García, Sarah Keller, Harley Betts, Kevin Cariou, Vicente Marchán, Gilles Gasser, Gonçalo J. L. Bernardes   +7 more
wiley   +2 more sources

Correction: Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice. [PDF]

Lipids Health Dis
Nan Y, Wang R, Zhao S, Han F, Wu WJ, Kong L, Fu N, Kong L, Yu J.   +8 more
europepmc   +1 more source

Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1 [PDF]

, 2018
Yang Jiao, Tanya Watts, Jing Xue, Bethany N. Hannafon, Wei‐Qun Ding   +4 more
openalex   +1 more source

Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real‐World Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Bilirubin is a breakdown product of erythrocytes and plays a crucial role in elimination of heme‐containing proteins. After its synthesis in the reticuloendothelial system, unconjugated bilirubin is released into plasma and taken up into the liver.
Ahenk Zeynep Sayin, Lars Kuepfer
wiley   +1 more source

The Heme Oxygenase/Biliverdin Reductase System as a Therapeutic Target to Counteract Cellular Senescence in Alzheimer's Disease. [PDF]

Antioxidants (Basel)
Mancuso C.
europepmc   +1 more source

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń, Julia Karbowska, Wiktoria Pietrowicz, Robert Stasiuk, Łukasz Drewniak   +4 more
wiley   +1 more source

The protective role of nuclear Heme oxygenase-1 in blood-spinal cord barrier after hypoxia in vitro. [PDF]

Sci Rep
Wang J, Wang H, Wang T, Zhang P, Cao Y, Yu T.   +5 more
europepmc   +1 more source

Changing Faces of Heme Oxygenases

Antioxidants & Redox Signaling, 2007
openaire   +3 more sources