Results 11 to 20 of about 60,693 (303)
Journal of Microbiology, Immunology and Infection, 2021 Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1
Wen-Lin Su +5 more
doaj +1 more source
Immunolocalization of heme oxygenase-1 in periodontal diseases
Indian Journal of Dental Research, 2014 Context: Chronic periodontitis is an inflammatory condition of supporting tissues initiated by organisms in dental plaque. The reactive oxygen species and free radicals mediate connective tissue destruction in periodontitis.
G Gayathri +3 more
doaj +1 more source
Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions
Brazilian Journal of Medical and Biological Research, 1999 Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes, including CNS and cardiovascular effects. But CO is also formed endogenously in mammalian tissues. Endogenously formed CO normally arises from heme degradation in a
R.A. Johnson, F. Kozma, E. Colombari
doaj +1 more source
Haematologica, 2015 Heme oxygenase-1 is critical for iron recycling during red blood cell turnover, whereas its impact on steady-state erythropoiesis and red blood cell lifespan is not known. We show here that in 8- to 14-week old mice, heme oxygenase-1 deficiency adversely
Stuart T. Fraser +13 more
doaj +1 more source
Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells. [PDF]
PLoS ONE, 2011 In mammalian cells, heme can be degraded by heme-oxygenases (HO). Heme-oxygenase 1 (HO-1) is known to be the heme inducible isoform, whereas heme-oxygenase 2 (HO-2) is the constitutive enzyme.
Liliane R Alves +10 more
doaj +1 more source
Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats [PDF]
Brazilian Journal of Medical and Biological Research, 2016 The heme oxygenase-carbon monoxide pathway has been shown to play an important role in many physiological processes and is capable of altering nociception modulation in the nervous system by stimulating soluble guanylate cyclase (sGC).
P.G. Carvalho-Costa +2 more
doaj +3 more sources
Innate Immunity, 2019 Our previous study indicated an important protective role of transient receptor potential melastatin 2 (TRPM2) in controlling bacterial clearance in macrophages during polymicrobial sepsis by regulating heme oxygenase-1.
XiaoWei Qian, Hao Cheng, XinZhong Chen
doaj +1 more source
Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features
Indonesian Journal of Obstetrics and Gynecology, 2016 Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty
Christian Homenta +2 more
doaj +1 more source
Heme Oxygenase and Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 Overproduction of reactive oxygen species under pathophysiological conditions, including dyslipidemia, hypertension, diabetes, and smoking, is integral in the development of cardiovascular diseases (CVD). The reactive oxygen species released from all types of vascular cells regulate various signaling pathways that mediate not only vascular inflammation
openaire +2 more sources
Haematologica, 2015 Sickle cell disease is a risk factor for invasive bacterial infections, and splenic dysfunction is believed to be the main underlying cause. We have previously shown that the liberation of heme in acute hemolysis can induce heme oxygenase-1 during ...
Ceri Evans +6 more
doaj +1 more source