Results 31 to 40 of about 120,535 (297)

Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2

BMC Complementary and Alternative Medicine, 2011
Background Both resveratrol and vitamin C (ascorbic acid) are frequently used in complementary and alternative medicine. However, little is known about the underlying mechanisms for potential health benefits of resveratrol and its interactions with ...
Hori Osamu, Hashida Koji, Döring Frank, Schmelzer Constance, Schrader Charlotte, Breckwoldt Dorothea, Boesch-Saadatmandi Christine, Wagner Anika E, Matsugo Seiichi, Rimbach Gerald   +9 more
doaj   +1 more source

Bacillus subtilis HmoB is a heme oxygenase with a novel structure [PDF]

BMB Reports, 2012
Iron availability is limited in the environment and mostbacteria have developed a system to acquire iron from hosthemoproteins. Heme oxygenase plays an important role bydegrading heme group and releasing the essential nutrientiron.
Seonghun Park, Sarah Choi, Jungwoo Choe
doaj   +1 more source

Heme oxygenase-1 in osteosarcoma

Journal of Cancer Research and Therapeutics, 2020
The present study was planned to analyze serum heme oxygenase-1 levels in osteosarcoma patients.Twenty five histopathologically confirmed cases of osteosarcoma localized without metastasis of all the ages attending the Orthopedic Clinics were included in the study group and twenty five patients having musculoskeletal pain (age and sex matched) served ...
Simmi, Kharb, M, Halder, Z S, Kundu
openaire   +2 more sources

Creation of novel pharmacological tools in heme oxygenase research [PDF]

, 2012
Aims: While great strides have been made in the elucidation of the physiological and pharmacological roles of heme oxygenases (HO) in experimental animals and humans, there is still an enormous potential for further research discoveries and their ...
Vukomanovic, Dragic, Hum, Maaike, Rahman, Mona N., McLaughlin, Brian E., Dercho , Ryan, Brien, James F., Vlahakis, Jason Z., Jia, Zongchao, Kinobe, Robert T., Szarek, Walter A., Roman, Gheorghe, Nakatsu, Kanji   +11 more
core   +1 more source

Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism.

PLoS ONE, 2017
Heme oxygenase from Leptospira interrogans is an important virulence factor. During catalysis, redox equivalents are provided to this enzyme by the plastidic-type ferredoxin-NADP+ reductase also found in L. interrogans.
Anabel Soldano, Sebastián Klinke, Lisandro H Otero, Mario Rivera, Daniela L Catalano-Dupuy, Eduardo A Ceccarelli   +5 more
doaj   +1 more source

Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children. [PDF]

, 2010
BACKGROUND: Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the ...
Sambo, Maria Rosário, Carla Benchimol, Marques, Maria Isabel, Nuno Sepúlveda, Carlos Penha-Gonçalves, Maria Rosário Sambo, Maria Isabel Marques, Stefan Mustafa, Sepúlveda, Nuno, Sepúlveda Nuno, Gonçalves Lígia, Trovoada, Maria Jesus, Mustafa Stefan, Rute Velosa, Marques Maria Isabel, Velosa, Rute, António Coutinho, Benchimol, Carla, Vatúsia Quinhentos, Sambo Maria Rosário, Quinhentos Vatúsia, Oswald Wagner, Taane G Clark, Benchimol Carla, Penha-Gonçalves Carlos, Penha-Gonçalves, Carlos, Gonçalves, Lígia, Mustafa, Stefan, Coutinho, António, Maria Jesus Trovoada, Coutinho António, Clark Taane G., Lígia Gonçalves, Trovoada Maria Jesus, Quinhentos, Vatúsia, Wagner, Oswald, Wagner Oswald, Taane G. Clark, Clark, Taane G, Velosa Rute, Clark, Taane G.   +40 more
core   +1 more source

A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells. [PDF]

PLoS ONE, 2012
We investigated the consequences of feeding with a Lactobacillus species on the immune environment in GALT, and the role of dendritic cells and heme oxygenase-1 in mediating these responses.
Khalil Karimi, Nalaayini Kandiah, Jessie Chau, John Bienenstock, Paul Forsythe   +4 more
doaj   +1 more source

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter

Haematologica, 2013
Induction of heme oxygenase-1, a stress-inducible enzyme with anti-inflammatory activity, reduces the immunogenicity of therapeutic factor VIII in experimental hemophilia A.
Yohann Repessé, Ivan Peyron, Jordan D Dimitrov, Suryasarathi Dasgupta, Elika Farrokhi Moshai, Catherine Costa, Annie Borel-Derlon, Benoit Guillet, Roseline D’Oiron, Achille Aouba, Chantal Rothschild, Johannes Oldenburg, Anna Pavlova, Srinivas V Kaveri, Sébastien Lacroix-Desmazes   +14 more
doaj   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

Angewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray, Sohan Hazra, Ryan W. Mull, Erinn M. O'Neill, Bo Li   +4 more
wiley   +2 more sources

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

Data in Brief, 2017
The data have been obtained from the Heme Oxygenase Database (HemeOxDB) and refined according to the 2D-QSAR requirements. These data provide information about a set of more than 380 Heme Oxygenase-1 (HO-1) inhibitors.
Emanuele Amata, Agostino Marrazzo, Maria Dichiara, Maria N. Modica, Loredana Salerno, Orazio Prezzavento, Giovanni Nastasi, Antonio Rescifina, Giuseppe Romeo, Valeria Pittalà   +9 more
doaj   +1 more source