Results 181 to 190 of about 29,780,783 (252)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, Volume 16, Issue 9, Page 1726-1740, September 2026.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Elevated serum heme oxygenase-1 in pediatric sickle cell disease: Insights from the SickleGenAfrica Network. [PDF]

Hemasphere
Sowa AM, Kudzi W, Paintsil V, Benneh-Akwasi Kuma AA, Segbefia CI, Olayemi E, Adjei DN, Bruce ANK, Gruen JR, Owusu-Dabo E, Ofori-Acquah SF, SickleGenAfrica Network.   +11 more
europepmc   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, Volume 38, Issue 52, 16 September 2026.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia. [PDF]

Front Mol Neurosci
Zou XY, Cai LY, Zhang J, Yuan Y, Song J, Hu ZD, Ruan XF, Peng R, Zhang XM.   +8 more
europepmc   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1961-1974, September 2026.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Fetuin-A and Heme Oxygenase 1 as Potential New Markers in the Diagnosis of Diabetic Kidney Disease. [PDF]

Int J Mol Sci
Król-Kulikowska M, Przyborska A, Miernikiewicz E, Roszykiewicz P, Roszykiewicz W, Banasik M, Kepinska M.   +6 more
europepmc   +1 more source

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

BMEMat, Volume 4, Issue 3, September 2026.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen, Haoyue Hu, Danyang Wang, Ying Wang, Zhibang Li, Xiaoyi Liu, Yandi Zhang, Junkun Feng, Weiwei Zhao, Kai Li, Qi‐Zhi Zhong, Shaohua Ge, Jianhua Li   +12 more
wiley   +1 more source

Ascorbate mitigates oxidative stress and hemin cytotoxicity in heme oxygenase-1 deficiency. [PDF]

J Biol Chem
Berendes LS, Schulze Westhoff P, Tobinski AM, Narvaez Pardo JA, Wingert V, Fobker M, Biskup S, Seelhöfer A, Van Marck V, Heitplatz B, Drell PT, Wittkowski H, Das AM, Hannibal L, Nowak WN, Józkowicz A, Klotz L, Varga G, Marquardt T, Park J.   +19 more
europepmc   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

The protective role of nuclear Heme oxygenase-1 in blood-spinal cord barrier after hypoxia in vitro. [PDF]

Sci Rep
Wang J, Wang H, Wang T, Zhang P, Cao Y, Yu T.   +5 more
europepmc   +1 more source