ABSTRACT Purpose This study aimed to evaluate the association between ramelteon use and mortality outcomes in patients with sepsis and cancer. The research question was whether ramelteon use is associated with reduced mortality in this high‐risk patient population. Methods A retrospective analysis of the MIMIC‐IV database was conducted.
Chendong Wang, Mingjie Liu, Jia Song
wiley +1 more source
Gnetum montanum extract attenuates lipopolysaccharide induced acute lung inflammation through Nrf2 and heme oxygenase 1 mediated redox modulation in macrophages. [PDF]
Pham DV +7 more
europepmc +1 more source
Longgu (fossilized bone) delivers a natural synergistic network of metal ions, Ca2+, Mg2+, Zn2+, Fe, Cu, and Mn2+ that collectively targets the interconnected pathologies of anxiety, depression, and insomnia. This multi‐ion system operates through coordinated mechanisms including ionostatic balance, cross‐pathway synergy, and systemic integration ...
Sun Xiujia +7 more
wiley +1 more source
Correction: The promoter T-413A variant and elevated enzyme levels of heme oxygenase-1 associated with an increased risk of polycystic ovarian syndrome. [PDF]
Wang Q +6 more
europepmc +1 more source
Chronic Paraquat Neurotoxicity and Dopaminergic Degeneration: A Mechanistic Review
Occurrence of Parkinson's disease (PD) based on several neurotoxins. Advanced and comprehensive mechanisms based on Paraquat‐induced PD. Mechanism of oxidative stress, ROS and RNS formation, and death of dopaminergic neurons. The modulation of genes and proteins by paraquat leads to Parkinsonism.
Saima Riaz +5 more
wiley +1 more source
Heme Oxygenase-1 Expression as a Prognostic Marker in Early-Stage HCC Undergoing Resection or Liver Transplantation. [PDF]
Cadar R +12 more
europepmc +1 more source
The edible insect Schistocerca gregaria exhibits potent antioxidant activity and represents a sustainable food source while contributing to pest management. Integrated in vitro antioxidant assays, molecular docking with heme oxygenase, cytotoxicity evaluation in human skin fibroblasts, and in vivo safety studies via different administration routes ...
Magda M. Aboelmahasen +5 more
wiley +1 more source
The promoter T-413A variant and elevated enzyme levels of heme oxygenase-1 associated with an increased risk of polycystic ovarian syndrome. [PDF]
Wang Q +6 more
europepmc +1 more source
Experimental flow chart of the attenuating and synergistic effects of RCH on TGTs in the treatment of rheumatoid arthritis. ABSTRACT Tripterygium Glycoside Tablets (TGTs) are primary drugs for rheumatoid arthritis (RA) but pose a risk of nephrotoxicity. Rubus chingii Hu (RCH) may enhance kidney function.
Cong Zhang +3 more
wiley +1 more source
Heme oxygenase-1 leads to cisplatin resistance in nasopharyngeal carcinoma by reducing oxidative stress and ferroptosis. [PDF]
Cheng Z +6 more
europepmc +1 more source

