Results 11 to 20 of about 51,151 (156)

Heme oxygenase-1 deletion affects stress erythropoiesis. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND:Homeostatic erythropoiesis leads to the formation of mature red blood cells under non-stress conditions, and the production of new erythrocytes occurs as the need arises.
Yu-An Cao   +5 more
doaj   +4 more sources

Immune-Related Functions of Heme Oxygenase-1

open access: yesAntioxidants, 2023
Heme oxygenase (HO)-1 is a well-known cytoprotective enzyme due to its enzymatic action, which involves the catalysis of heme into anti-apoptotic and antioxidant molecules such as bilirubin, biliverdin and CO [...]
Elias A. Lianos, Maria G. Detsika
doaj   +4 more sources

Heme oxygenase-1, oxidation, inflammation and atherosclerosis [PDF]

open access: yesFrontiers in Pharmacology, 2012
Atherosclerosis is an inflammatory process of the vascular wall characterized by the infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low density lipoproteins and induction of oxidative stress play a major role in ...
Jesus A Araujo, Min eZhang, Fen eYin
doaj   +3 more sources

Heme oxygenase-1 in osteosarcoma

open access: yesJournal of Cancer Research and Therapeutics, 2020
The present study was planned to analyze serum heme oxygenase-1 levels in osteosarcoma patients.Twenty five histopathologically confirmed cases of osteosarcoma localized without metastasis of all the ages attending the Orthopedic Clinics were included in the study group and twenty five patients having musculoskeletal pain (age and sex matched) served ...
Simmi, Kharb, M, Halder, Z S, Kundu
openaire   +2 more sources

Pharmacological Significance of Heme Oxygenase 1 in Prostate Cancer

open access: yesCurrent Issues in Molecular Biology, 2023
Heme oxygenase 1 (HO-1) is a detoxifying antioxidant microsomal enzyme that regulates inflammation, apoptosis, cell proliferation, and angiogenesis in prostate cancer (PCa).
Mohamed Ben-Eltriki   +3 more
doaj   +1 more source

Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2016
Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty
Christian Homenta   +2 more
doaj   +1 more source

Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

open access: yesJournal of Microbiology, Immunology and Infection, 2021
Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1
Wen-Lin Su   +5 more
doaj   +1 more source

Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice

open access: yesHaematologica, 2015
Heme oxygenase-1 is critical for iron recycling during red blood cell turnover, whereas its impact on steady-state erythropoiesis and red blood cell lifespan is not known. We show here that in 8- to 14-week old mice, heme oxygenase-1 deficiency adversely
Stuart T. Fraser   +13 more
doaj   +1 more source

Immunolocalization of heme oxygenase-1 in periodontal diseases

open access: yesIndian Journal of Dental Research, 2014
Context: Chronic periodontitis is an inflammatory condition of supporting tissues initiated by organisms in dental plaque. The reactive oxygen species and free radicals mediate connective tissue destruction in periodontitis.
G Gayathri   +3 more
doaj   +1 more source

Transient receptor potential melastatin 2–mediated heme oxygenase-1 has a role for bacterial clearance by regulating autophagy in peritoneal macrophages during polymicrobial sepsis

open access: yesInnate Immunity, 2019
Our previous study indicated an important protective role of transient receptor potential melastatin 2 (TRPM2) in controlling bacterial clearance in macrophages during polymicrobial sepsis by regulating heme oxygenase-1.
XiaoWei Qian, Hao Cheng, XinZhong Chen
doaj   +1 more source

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