Results 11 to 20 of about 29,780,783 (252)

Immunolocalization of heme oxygenase-1 in periodontal diseases

Indian Journal of Dental Research, 2014
Context: Chronic periodontitis is an inflammatory condition of supporting tissues initiated by organisms in dental plaque. The reactive oxygen species and free radicals mediate connective tissue destruction in periodontitis.
G Gayathri, S Muthukumar, Leena Dennis Joseph, R Suresh   +3 more
doaj   +2 more sources

Immune-Related Functions of Heme Oxygenase-1

Antioxidants, 2023
Heme oxygenase (HO)-1 is a well-known cytoprotective enzyme due to its enzymatic action, which involves the catalysis of heme into anti-apoptotic and antioxidant molecules such as bilirubin, biliverdin and CO [...]
Elias A. Lianos, Maria G. Detsika
doaj   +2 more sources

Heme oxygenase 1 overexpression increases iron fluxes in Caco-2 cells [PDF]

Biological Research, 2006
Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous Fe.
MARÍA JOSE MENDIBURO, SEBASTIÁN FLORES, FERNANDO PIZARRO, MIGUEL ARREDONDO   +3 more
doaj   +1 more source

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis [PDF]

, 2023
The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. HMOX1 cytoprotection is imperative to limit oxidative stress.
Rachitha Singhabahu, Kodagoda Gamage, Sujani M, Sujani M. Kodagoda Gamage, Gopalan, Vinod, Kodagoda Gamage, SM, Singhabahu, Rachitha, Singhabahu, R, Vinod Gopalan, Gopalan, V   +8 more
core   +1 more source

Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen risk and cardiovascular health study) [PDF]

, 2009
Background Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide.
Hoffmann Michael M, Hoffmann, Michael Marcus, März Winfried, Boehm Bernhard O, Wellnitz Britta, Karl Winkler, Bernhard O Boehm, Bernhard R Winkelmann, März, Winfried, Winkelmann Bernhard R, Winkler Karl, Hoffmann, Michael M., Seelhorst Ursula, Ursula Seelhorst, Seelhorst, Ursula, Britta Wellnitz, Böhm, Bernhard O., Böhm, Bernhard Otto, Michael M Hoffmann, Lüblinghoff Nicola, Lüblinghoff, Nicola, Winkelmann, Bernhard Rudolf, Winfried März, Winkler, Karl, Nicola Lüblinghoff, Winkelmann, Bernhard R., Wellnitz, Britta   +26 more
core   +2 more sources

HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children. [PDF]

, 2012
Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression.
Madi Njie (177625), Walther, Brigitte, Cunnington, A., De Caul, A, Sebastian Weis, Ebonyi, A., Deininger Susanne, Aka Peter, Deininger, S., Peter Aka, Takem, Ebako N, Predazzi, Irene M, Conway David J., Predazzi, IM, Cunnington, Aubrey, Walther, Michael, Conway, DJ, Aubrey Cunnington, Njie, M., Predazzi, I. M., Weis Sebastian, Augustine Ebonyi (177659), Sarah Rowland-Jones, Walther Michael, Amambua-Ngwa, A., Sarah Rowland-Jones (74678), Scott M. Williams (177668), Robert Walton, Susanne Deininger (173844), Sirugo, G, Cunnington Aubrey, Njie, Madi, Williams Scott M., Sirugo, Giorgio, Weis, S, Augustine Ebonyi, Walton Robert, Aka, P, Aka, P., Rowland-Jones Sarah, Williams, Scott M, Williams, S. M., Ebonyi, A, Alfred Amambua-Ngwa (122336), Weis, Sebastian, De Caul, Adam, Williams, SM, Sebastian Weis (161447), Amambua-Ngwa Alfred, Takem Ebako N., Deininger, Susanne, Adam De Caul (177612), Giorgio Sirugo, Ebako N. Takem (177656), Amambua-Ngwa, A, Walton, Robert T., Ebonyi, Augustine, Alfred Amambua-Ngwa, Madi Njie, Michael Walther, Rowland-Jones, S., Giorgio Sirugo (62489), Aka, Peter, Walton, R, Njie, M, De Caul Adam, Njie Madi, Rowland-Jones, Sarah, Takem, EN, Predazzi Irene M., Takem, E. N., Robert Walton (177664), Amambua-Ngwa, Alfred, Conway, D. J., Adam De Caul, Walther, B., Weis, S., Deininger, S, Susanne Deininger, Aubrey Cunnington (177640), Conway, David J, Peter Aka (177618), Sirugo, G., Ebako N Takem, David J Conway, David J. Conway (34880), de Caul, A., Irene M. Predazzi (177634), Brigitte Walther (130764), Walther, M, Walther, M., Walther Brigitte, Walton, Robert, Cunnington, A, Scott M Williams, Irene M Predazzi, Sirugo Giorgio, Walther, B, Rowland-Jones, S, Brigitte Walther, Michael Walther (130767), Ebonyi Augustine   +101 more
core   +1 more source

Clinical Significance of Heme Oxygenase 1 in Tumor Progression

Antioxidants, 2021
Heme oxygenase 1 (HO-1) plays a key role in cell adaptation to stressors through the antioxidant, antiapoptotic, and anti-inflammatory properties of its metabolic products.
Mariapaola Nitti, Caterina Ivaldo, Nicola Traverso, Anna Lisa Furfaro   +3 more
doaj   +1 more source

Early Serum Heme Oxygenase-1, Soluble Vascular Endothelial Growth Factor Receptor-1, and B-Cell Lymphoma/Leukemia-2 Levels and Unfavorable Obstetric Outcomes

Gynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVE: To examine early pregnancy levels of serum heme oxygenase-1, soluble vascular endothelial growth factor receptor-1, B-cell lymphoma/leukemia-2 in relation to unfavorable pregnancy outcomes, including preeclampsia, fetal growth restriction ...
Havva Sutcu, G. Fusun Varol, Cihan Inan, Isil Uzun, N.Cenk Sayin   +4 more
doaj   +1 more source

Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features

Indonesian Journal of Obstetrics and Gynecology, 2016
Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty
Christian Homenta, John J Wantania, Juneke J Kaeng   +2 more
doaj   +1 more source

Nuclear Factor-κB-Independent Anti-Inflammatory Action of Salicylate in Human Endothelial Cells [PDF]

, 2006
In contrast to aspirin, salicylate, its active metabolite, possesses profound anti-inflammatory properties without blocking cyclooxygenase. Inhibition of the transcription factor nuclear factor-κB (NF-κB) has been discussed to play a role in the anti ...
Blumenthal, Signe B., Vollmar, Angelika M., Kiemer, Alexandra K., Zahler, Stefan, Fürst, Robert   +4 more
core   +1 more source