Results 31 to 40 of about 51,151 (156)

Human AKI and Heme Oxygenase-1 [PDF]

Journal of the American Society of Nephrology, 2012
Findings derived from animal models of AKI gain clinical credence and appeal when translational studies corroborate their occurrence in human AKI. In the current issue of JASN , Zager et al.
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Heme Oxygenase-1 [PDF]

Circulation, 2006
Schmid and coworkers1 were the first to report on the presence of heme oxygenase (HO) in liver microsomes capable of degrading heme to bilirubin, and this activity was subsequently dissociated from cytochrome P-450.2,3 HO catalyzes the first and rate-limiting step in the oxidative degradation of heme (Fe-protoporphyrin-IX) to carbon monoxide (CO ...
Roland, Stocker, Mark A, Perrella
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Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression

Neural Regeneration Research
[INLINE:1] Previous studies have reported upregulation of heme oxygenase-1 in different central nervous system injury models. Heme oxygenase-1 plays a critical anti-inflammatory role and is essential for regulating cellular redox homeostasis.
Zhihua Wang, Wu Zhou, Zhixiong Zhang, Lulu Zhang, Meihua Li   +4 more
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Strontium Ranelate Elevates Expression of Heme Oxygenase-1 and Decreases Alveolar Bone Loss in Rats

eJournal of Oral Maxillofacial Research, 2018
Objectives: The purpose of this study was to determine the effects of strontium ranelate on ligature-induced periodontitis in rats and assess the putative involvement of heme oxygenase-1 (HO-1) pathway in these effects.
Ricardo Basto Souza, Francisco Isaac Fernandes Gomes, Karuza Maria Alves Pereira, Paula Goes Pinheiro Dutra, Rodrigo Maranguape Silva da Cunha, Hellíada Vasconcelos Chaves, Mirna Marques Bezerra   +6 more
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Heme Oxygenase-1 Deficiency [PDF]

Indian Pediatrics, 2021
Renji, Soumya, Shah, Nitin, Madkaikar, Manisha   +2 more
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Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury

SAGE Open Medicine
Objective: Ischemia-reperfusion injury exacerbates myocardial damage and affects the prognosis of patients with ST-elevation myocardial infarction. This study investigates the potential cytoprotective effects of hemin in an in vitro cardiomyocyte model ...
Zuoyan Wang, Wei Liu
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Production of Transgenic Micro-Pig Expressing Human Heme Oxygenase 1

Journal of Animal Reproduction and Biotechnology, 2015
Xenotransplantation of pig islet regarded as a good alternative to allotransplantation. However, cellular death mediated by hypoxia-reoxygenation injury after transplantation disturb success of this technique.
Ok Jae Koo, Hyun Ju Oh, Byeong Chun Lee
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A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells. [PDF]

PLoS ONE, 2012
We investigated the consequences of feeding with a Lactobacillus species on the immune environment in GALT, and the role of dendritic cells and heme oxygenase-1 in mediating these responses.
Khalil Karimi, Nalaayini Kandiah, Jessie Chau, John Bienenstock, Paul Forsythe   +4 more
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Heme Oxygenase-1 Protects the Heart [PDF]

Circulation Research, 2001
The seminal discovery of nitric oxide (NO) in the 1980s unraveled the novel concept that an endogenous production of a gaseous substance such as NO can impart diverse and critical functional effects on a wide spectrum of biological and pathological processes.
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Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1

Neural Regeneration Research
Interfering with the ferroptosis pathway is a new strategy for the treatment of spinal cord injury. Fibroblast growth factor 21 can inhibit ferroptosis and promote neurofunctional recovery, while heme oxygenase-1 is a regulator of iron and reactive ...
Qi Gu, Weiping Sha, Qun Huang, Jin Wang, Yi Zhu, Tianli Xu, Zhenhua Xu, Qiancheng Zhu, Jianfei Ge, Shoujin Tian, Xiaolong Lin   +10 more
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