Results 71 to 80 of about 29,780,783 (252)
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Triveni Kodi +3 more
wiley +1 more source
Heme oxygenase-1, oxidation, inflammation and atherosclerosis
Frontiers in Pharmacology, 2012 Atherosclerosis is an inflammatory process of the vascular wall characterized by the infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low density lipoproteins and induction of oxidative stress play a major role in ...
Jesus A Araujo, Min eZhang, Fen eYin
doaj +1 more source
Frontiers in Neurology, 2018 Intracerebral hemorrhage (ICH) is a fatal acute cerebrovascular disease, with a high morbidity and mortality. Following ICH, erythrocytes release heme and several of its metabolites, thereby contributing to brain edema and secondary brain damage.
Qian-Qian Li +4 more
doaj +1 more source
Prevention of Ischemia-Reperfusion Injury in the Rat Liver by Atrial Natriuretic Peptide [PDF]
, 2002 This work characterizes the protective effects of ANP preconditioning in ischemia-reperfusion injury of the isolated perfused rat liver. It was of particular interest to evaluate the influence of ANP on the mode of cell death occurring during cold ...
Gerwig, Tobias
core +1 more source
Haematologica, 2011 Background Sickle cell disease, a genetic red cell disorder inherited in an autosomal recessive manner, occurs throughout the world. Hepatic dysfunction and liver damage may be present in sickle cell disease, but the pathogenesis of these conditions is ...
Angela Siciliano +10 more
doaj +1 more source
Down-regulation of heme oxygenase-1 by SVCV infection
, 2012 Heme oxygenase (HO-1) is a cytoprotective enzyme that plays a critical role in defending the body against oxidant-induced injury during inflammatory processes.
Shi, Zhengli +6 more
core +1 more source
Biomedical and Biotechnology Research Journal, 2019 Background: Human immunodeficiency virus (HIV) infection is an important infection seen worldwide. HIV-infected patients usually have impaired immune function and get infected with other concurrent infections.
Won Sriwijitalai, Viroj Wiwanitkit
doaj +1 more source
Inductive transcription and protective role of fish heme oxygenase-1 under hypoxic stress
, 2008 Heme oxygenase-1 is the rate-limiting enzyme in the degradation of heme into biliverdin, carbon monoxide and free divalent iron. In this study, we cloned heme oxygenase isoform 1 (CaHO-1) from a hypoxia-tolerant teleost fish Carassius auratus.
Wang, Dan +4 more
core +1 more source
BMEMat, EarlyView.This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang +7 more
wiley +1 more source
Astrocyte-specific heme oxygenase-1 hyperexpression attenuates heme-mediated oxidative injury
Neurobiology of Disease, 2007 In prior studies, we have observed that HO activity protects astrocytes from heme-mediated injury, but paradoxically increases neuronal injury. In this study, we tested the hypothesis that an adenovirus encoding the human HO-1 gene driven by an enhanced ...
Luna Benvenisti-Zarom, Raymond F. Regan
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