Results 1 to 10 of about 3,405 (218)

Behind the Optimization of the Sensor Film: Bioconjugation of Triangular Gold Nanoparticles with Hemoproteins for Sensitivity Enhancement of Enzymatic Biosensors [PDF]

open access: yesBiosensors, 2023
Electrochemical biosensors are widely used in a multitude of applications, such as medical, nutrition, research, among other fields. These sensors have been historically used and have not undergone many changes in terms of the involved electrochemical ...
Miriam Chávez   +6 more
doaj   +2 more sources

Bio-Electroanalysis Performance of Heme Redox-Center for π-π Interaction Bonding of a Methylene Blue-Graphene Modified Electrode [PDF]

open access: yesNanomaterials, 2023
Hemeprotein detection has motivated extensive research on the direct reaction of a heme molecule and a redox dye. The present study used methylene blue as both donor and acceptor for a redox reaction.
Porntip Khownarumit   +5 more
doaj   +2 more sources

Low levels of nitric oxide promotes heme maturation into several hemeproteins and is also therapeutic [PDF]

open access: yesRedox Biology, 2022
Nitric oxide (NO) is a signal molecule and plays a critical role in the regulation of vascular tone, displays anti-platelet and anti-inflammatory properties.
Arnab Ghosh   +8 more
doaj   +2 more sources

Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches [PDF]

open access: yesCells, 2022
The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj   +2 more sources

Cardiolipin Membranes Promote Cytochrome c Transformation of Polycyclic Aromatic Hydrocarbons and Their In Vivo Metabolites [PDF]

open access: yesMolecules
The catalytic properties of cytochrome c (Cc) have captured great interest in respect to mitochondrial physiology and apoptosis, and hold potential for novel enzymatic bioremediation systems.
João Lopes   +4 more
doaj   +2 more sources

A Bioinformatics-Assisted Review on Iron Metabolism and Immune System to Identify Potential Biomarkers of Exercise Stress-Induced Immunosuppression

open access: yesBiomedicines, 2022
The immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of this bioinformatics-assisted review was twofold; (i) to update the current knowledge of Fe metabolism and its relationship to the immune system, and (ii) to ...
Diego A. Bonilla   +9 more
doaj   +1 more source

Recent Development of the Molecular and Cellular Mechanisms of Hydrogen Sulfide Gasotransmitter

open access: yesAntioxidants, 2022
Hydrogen sulfide has been recently identified as the third biological gasotransmitter, along with the more well studied nitric oxide (NO) and carbon monoxide (CO). Intensive studies on its potential as a therapeutic agent for cardiovascular, inflammatory,
Jianyun Liu   +7 more
doaj   +1 more source

The Balancing of Peroxynitrite Detoxification between Ferric Heme-Proteins and CO2: The Case of Zebrafish Nitrobindin

open access: yesAntioxidants, 2022
Nitrobindins (Nbs) are all-β-barrel heme proteins and are present in prokaryotes and eukaryotes. Although their function(s) is still obscure, Nbs trap NO and inactivate peroxynitrite.
Giovanna De Simone   +4 more
doaj   +1 more source

Recent Approaches for Manipulating Globin Gene Expression in Treating Hemoglobinopathies

open access: yesFrontiers in Genome Editing, 2021
Tissue oxygenation throughout life depends on the activity of hemoglobin (Hb) one of the hemeproteins that binds oxygen in the lungs and secures its delivery throughout the body.
Claudio Mussolino   +2 more
doaj   +1 more source

New insights into the role of heme oxygenase-1 in acute kidney injury

open access: yesKidney Research and Clinical Practice, 2020
Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and serum, decreased urine output, and impaired glomerular filtration rate.
Meryl Nath, Anupam Agarwal
doaj   +1 more source

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