Results 21 to 30 of about 34,452 (261)

Exogenous hemin improves Cd2+ tolerance and remediation potential in Vigna radiata by intensifying the HO-1 mediated antioxidant defence system

open access: yesScientific Reports, 2021
The present study evaluated the effects of exogenous hemin on cadmium toxicity in terms of metal accretion and stress resilience in Vigna radiata L. (Wilczek).
Lovely Mahawar   +4 more
semanticscholar   +1 more source

Hemin as a novel candidate for treating COVID-19 via heme oxygenase-1 induction

open access: yesScientific Reports, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease-19 (COVID-19). More than 143 million cases of COVID-19 have been reported to date, with the global death rate at 2.13%. Currently, there are no
Dong-Hwi Kim   +11 more
semanticscholar   +1 more source

Hemin Improves Insulin Sensitivity in Skeletal Muscle in High Fat–Fed Mice

open access: yesJournal of Pharmacological Sciences, 2014
.: The present study examined whether hemin could prevent the development of high-fat diet–induced insulin resistance in the liver and skeletal muscle using a hyperinsulinemic-euglycemic clamp.
Tae-Jin Ju   +6 more
doaj   +1 more source

Exogenous Hemin Confers Cadmium Tolerance by Decreasing Cadmium Accumulation and Modulating Water Status and Matter Accumulation in Maize Seedlings

open access: yesAgronomy, 2021
Cadmium (Cd) contamination harms plant growth and human health. The application of hemin (ferroprotoporphyrin IX) can effectively relieve abiotic stresses in plants.
Xiaoming Liu   +3 more
doaj   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2-Mediated Acetylation of Hexokinase-2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage. [PDF]

open access: yesAdv Sci (Weinh)
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Jiang Z   +9 more
europepmc   +2 more sources

Hemin-doped metal–organic frameworks based nanozyme electrochemical sensor with high stability and sensitivity for dopamine detection

open access: yesRSC Advances, 2021
This study reports a new type of artificial nanozyme based on Hemin-doped-HKUST-1 (HKUST-1, also referred to as MOF-199; a face-centered-cubic MOF containing nanochannels) as a redox mediator for the detection of dopamine (DA).
K. Kang   +7 more
semanticscholar   +1 more source

Biological Oxidations and Nitrations Promoted by the Hemin–Aβ16 Complex

open access: yesAntioxidants, 2023
Both β-amyloid (Aβ) peptides and oxidative stress conditions play key roles in Alzheimer’s disease. Hemin contributes to the development of the disease as it possesses redox properties and its level increases in pathological conditions or traumatic brain
Silvia De Caro   +4 more
doaj   +1 more source

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

open access: yesAdvances in Materials, 2020
The fabrication of biomimetic catalysts as substituents for enzymes is of critical interest in the field due to the problems associated with the extraction, purification, and storage of enzymes in sensing applications.
A. M. Alsharabasy   +2 more
semanticscholar   +1 more source

Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron

open access: yesFrontiers in Physiology, 2017
Hemin plays a key role in mediating secondary neuronal injury after intracerebral hemorrhage (ICH) and the cell toxicity of hemin is thought to be due to iron that is liberated when hemin is degraded.
Yu-Fu Zhou   +11 more
doaj   +1 more source

Once-monthly hemin suppresses inflammatory and autoreactive CD4+ T cell responses to robustly ameliorate experimental rheumatoid arthritis

open access: yesiScience, 2021
Summary: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that would permanently damage the affected joints. Unfortunately, a large proportion of RA patients fail to respond adequately to current treatments. Here, repurposing hemin and its
Bingzhi Sun   +7 more
doaj   +1 more source

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