Results 21 to 30 of about 22,100 (162)

Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron

Frontiers in Physiology, 2017
Hemin plays a key role in mediating secondary neuronal injury after intracerebral hemorrhage (ICH) and the cell toxicity of hemin is thought to be due to iron that is liberated when hemin is degraded.
Yu-Fu Zhou, Chao Zhang, Chao Zhang, Guang Yang, Zhong-Ming Qian, Meng-Wan Zhang, Meng-Wan Zhang, Juan Ma, Juan Ma, Fa-Li Zhang, Fa-Li Zhang, Ya Ke   +11 more
doaj   +1 more source

Hemin-induced suicidal erythrocyte death [PDF]

Annals of Hematology, 2009
Several diseases, such as malaria, sickle cell disease, and ischemia/reperfusion may cause excessive formation of hemin, which may in turn trigger hemolysis. A variety of drugs and diseases leading to hemolysis triggers suicidal erythrocyte death or eryptosis, i.e., cell membrane scrambling and cell shrinkage.
Sergios, Gatidis, Michael, Föller, Florian, Lang   +2 more
openaire   +2 more sources

Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

mSystems, 2023
Periodontal disease is a chronic inflammatory disease in which the oral pathogen Porphyromonas gingivalis plays an important role. Porphyromonas gingivalis expresses virulence determinants in response to higher hemin concentrations, but the underlying ...
Ricardo Costeira, Joseph Aduse-Opoku, Jon J. Vernon, Francisco Rodriguez-Algarra, Susan Joseph, Deirdre A. Devine, Philip D. Marsh, Vardhman Rakyan, Michael A. Curtis, Jordana T. Bell   +9 more
doaj   +1 more source

Comparison of Characteristics and DNAzyme Activity of G4–Hemin Conjugates Obtained via Two Hemin Attachment Methods

Molecules, 2018
Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman, Krzysztof Żukowski, Bernard Juskowiak   +2 more
doaj   +1 more source

Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis

Redox Biology, 2023
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); however ...
Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub   +16 more
doaj   +1 more source

HemU and TonB1 contribute to hemin acquisition in Stenotrophomonas maltophilia

Frontiers in Cellular and Infection Microbiology
IntroductionThe hemin acquisition system is composed of an outer membrane TonB-dependent transporter that internalizes hemin into the periplasm, periplasmic hemin-binding proteins to shuttle hemin, an inner membrane transporter that transports hemin into
Chun-Hsing Liao, Chun-Hsing Liao, Hsu-Feng Lu, Ching-Wei Yang, Ting-Yu Yeh, Yi-Tsung Lin, Yi-Tsung Lin, Tsuey-Ching Yang   +7 more
doaj   +1 more source

Hemin uptake in Porphyromonas gingivalis: Omp26 is a hemin-binding surface protein [PDF]

Journal of Bacteriology, 1993
A 26-kDa outer membrane protein (Omp26) has been proposed to play a role in hemin acquisition by Porphyromonas gingivalis (T. E. Bramanti and S. C. Holt, J. Bacteriol. 174:5827-5839, 1992). We studied [55Fe]hemin uptake in P. gingivalis grown under conditions of hemin starvation (Omp26 expressed on the outer membrane surface) and hemin excess (Omp26 ...
T E, Bramanti, S C, Holt
openaire   +2 more sources

Functional characterization of RhuB as a second TonB2-dependent hemin receptor in Riemerella anatipestifer CH-1

Microbiology Spectrum
In the previous study, it was shown that Riemerella anatipestifer (R. anatipestifer, RA), a pathogen in ducks and some other birds, encodes a hemin uptake system. The R.
Mengying Wang, Siyi Wang, Mingshu Wang, Dekang Zhu, Renyong Jia, Shun Chen, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Mafeng Liu, Anchun Cheng   +12 more
doaj   +1 more source

Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism

Frontiers in Chemistry, 2020
The indirect determination of the most used herbicide worldwide, glyphosate, was achieved by the SERS technique using hemin chloride as the reporter molecule.
Karen A. López-Castaños, Luis A. Ortiz-Frade, Erika Méndez, Enrique Quiroga-González, Miguel A. González-Fuentes, Alia Méndez-Albores   +5 more
doaj   +1 more source

Hemin treatment drives viral reactivation and plasma cell differentiation of EBV latently infected B cells.

PLoS Pathogens, 2023
Epstein-Barr virus (EBV) and Plasmodium falciparum have a well described role in the development of endemic Burkitt lymphoma (BL), yet the mechanisms involved remain unknown.
Anna M Burnet, Tonya Brunetti, Rosemary Rochford   +2 more
doaj   +1 more source