Results 11 to 20 of about 2,500 (188)

Biophysical Characterization of Shrimp Hemocyanins: Stability and Emerging Biotechnological Applications. [PDF]

Biomolecules
Hemocyanins are oxygen-transporting proteins found in crustaceans and other arthropods, playing key roles in immune defense and metabolic regulation. Due to their stability and bioactive properties, Hcs have gained increasing interest in biotechnological
Ramos L, Souza CO, Sebastião Í, Bertini G, Carvalho FAO, da Silva RMG, Vilanculo EM, Pereira JS, Santiago PS.   +8 more
europepmc   +2 more sources

Modified Hemocyanins from Rapana thomasiana and Helix aspersa Exhibit Strong Antitumor Activity in the B16F10 Mouse Melanoma Model. [PDF]

Mar Drugs
Melanoma is one of the most common tumors worldwide, and new approaches and antitumor drugs for therapy are being investigated. Among the promising biomolecules of natural origin for antitumor research are gastropodan hemocyanins—highly immunogenic ...
Stoyanova E, Mihaylova N, Ralchev N, Bradyanova S, Manoylov I, Raynova Y, Idakieva K, Tchorbanov A.   +7 more
europepmc   +2 more sources

Classification of polyphenol oxidases shows ancient gene duplication leading to two distinct enzyme types. [PDF]

iScience
Summary: Polyphenol oxidases (PPOs) are coupled binuclear copper proteins that catalyze the oxidation of phenols. New functions of PPOs are continuously being discovered, latest with several fungal o-methoxy phenolases, which are active on lignin-derived
Meitil IKS, de O G Silva C, Pedersen AG, Agger JW.   +3 more
europepmc   +2 more sources

Venomics of Scorpion <i>Ananteris platnicki</i> (Lourenço, 1993), a New World Buthid That Inhabits Costa Rica and Panama. [PDF]

Toxins (Basel)
Ananteris is a scorpion genus that inhabits dry and seasonal areas of South and Central America. It is located in a distinctive morpho-group of Buthids, the ‘Ananteris group’, which also includes species distributed in the Old World.
Díaz C, Lomonte B, Chang-Castillo A, Bonilla F, Alfaro-Chinchilla A, Triana F, Angulo D, Fernández J, Sasa M.   +8 more
europepmc   +2 more sources

A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor activity in melanoma. [PDF]

PLoS ONE, 2014
Hemocyanins, the huge oxygen-transporting glycoproteins of some mollusks, are used as immunomodulatory proteins with proven anti-cancer properties. The biodiversity of hemocyanins has promoted interest in identifying new anti-cancer candidates with ...
Sergio Arancibia, Cecilia Espinoza, Fabián Salazar, Miguel Del Campo, Ricardo Tampe, Ta-Ying Zhong, Pablo De Ioannes, Bruno Moltedo, Jorge Ferreira, Ed C Lavelle, Augusto Manubens, Alfredo E De Ioannes, María Inés Becker   +12 more
doaj   +1 more source

Influence of Temperature, Hypercapnia, and Development on the Relative Expression of Different Hemocyanin Isoforms in the Common Cuttlefish Sepia officinalis [PDF]

, 2012
The cuttlefish Sepia officinalis expresses several hemocyanin isoforms with potentially different pH optima, indicating their reliance on efficient pH regulation in the blood.
Gutowska, Magdalena A., Hu, Marian Y.A., Lieb, Bernhard, Lucassen, Magnus, Mark, Felix Christopher, Melzner, Frank, Pörtner, Hans-Otto, Strobel, Anneli   +7 more
core   +1 more source

TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals

Frontiers in Immunology, 2019
Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) and driving immune responses ...
José M. Jiménez, Michelle L. Salazar, Sergio Arancibia, Javiera Villar, Fabián Salazar, Fabián Salazar, Gordon D. Brown, Ed C. Lavelle, Luisa Martínez-Pomares, Jafet Ortiz-Quintero, Sergio Lavandero, Augusto Manubens, María Inés Becker, María Inés Becker   +13 more
doaj   +1 more source

N-Terminal Amino Acid Sequence Comparison of Asian Horseshoe Crab Hemocyanins: Immunologically Identical Hemocyanin Subunits Are Orthologous in Asian Horseshoe Crabs [PDF]

, 1998
Each hemocyanin of the 3 Asian horseshoe crabs is composed of 6 immunologically different subunits, each subunit of which is immunologically identical with the comparable subunits of 2 other species.
Murayama Hiroshi, Sugita Hiroaki, 杉田 博昭   +2 more
core   +1 more source

Jumping on the Edge—First Evidence for a 2 × 6-meric Hemocyanin in Springtails

Biomolecules, 2019
Hemocyanins are respiratory dioxygen carrier proteins found in many arthropods including ancient terrestrial species such as spiders and scorpions as well as marine horseshoe crabs.
Juliane Schmidt, Heinz Decker, Michael T. Marx   +2 more
doaj   +1 more source

Hemocyanin facilitates lignocellulose digestion by wood-boring marine crustaceans [PDF]

, 2018
Woody (lignocellulosic) plant biomass is an abundant renewable feedstock, rich in polysaccharides that are bound into an insoluble fiber composite with lignin.
Azevedo, Eduardo Ribeiro de, Besser, Katrin, Bruce, Neil C., Cragg, Simon M., Cruz Garcia, Lourdes, Cunha, Giovanni Paro da, Dowle, Adam, Dupree, Paul, Dupree, Ray, Eborall, William S., Elias, Luisa, Filgueiras, Jefferson G., Gomez, Leonardo D., Kern, Marcelo, Li, Yi, Malyon, Graham P., McQueen-Mason, Simon J., Mohamad, Shaza E., Page, Samuel J., Pesante, Giovanna, Polikarpov, Igor, Sabbadin, Federico, Steele-King, Clare   +22 more
core   +4 more sources