Results 31 to 40 of about 2,500 (188)
Sublethal Behavioral and Physiological Effects of the Biomedical Bleeding Process on the American Horseshoe Crab, Limulus polyphemus [PDF]
, 2013 The hemolymph of the American horseshoe crab, Limulus polyphemus, is harvested from over 500,000 animals annually to produce Limulus amebocyte lysate (LAL), a medically important product used to detect pathogenic bacteria. Declining abundance of spawning
Anderson, Rebecca L. +2 more
core +3 more sources
Marine Drugs, 2022 Hemocyanins present in the hemolymph of invertebrates are multifunctional proteins that are responsible for oxygen transport and play crucial roles in the immune system.
Chun Yuan +6 more
doaj +1 more source
Cryo-EM structure of isomeric molluscan hemocyanin triggered by viral infection. [PDF]
PLoS ONE, 2014 Hemocyanins (Hcs) of arthropods and mollusks function not only as oxygen transporters, but also as phenoloxidases (POs). In invertebrates, PO is an important component in the innate immune cascade, where it functions as the initiator of melanin synthesis,
Hongtao Zhu +6 more
doaj +1 more source
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito +9 more
wiley +2 more sources
Frontiers in Marine Science, 2019 The functional diversity of crustacean hemocyanins is broad, encompassing O2 delivery, innate immune response, metabolite storage, and osmolyte balance, all in a heterogeneous protein structure.
Jason Wang +2 more
doaj +1 more source
Calorimetric Study of Helix aspersa Maxima Hemocyanin Isoforms
Journal of Analytical Methods in Chemistry, 2018 The thermal unfolding of hemocyanin isoforms, β-HaH and αD+N-HaH, isolated from the hemolymph of garden snails Helix aspersa maxima, was studied by means of differential scanning calorimetry (DSC). One transition, with an apparent transition temperature (
Svetla Todinova +2 more
doaj +1 more source
Diverse immune functions of hemocyanins
Developmental & Comparative Immunology, 2014 Substantial evidence gathered recently has revealed the multiple functionalities of hemocyanin. Contrary to previous claims that this ancient protein is involved solely in oxygen transport within the hemolymph of invertebrates, hemocyanin and hemocyanin-derived peptides have been linked to key aspects of innate immunity, in particular, antiviral and ...
Coates, Christopher, Nairn, Jacqueline
openaire +4 more sources
A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies
Analysis &Sensing, EarlyView.An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro +7 more
wiley +1 more source
Molecular Evolution of the Oxygen-Binding Hemerythrin Domain. [PDF]
PLoS ONE, 2016 BACKGROUND:The evolution of oxygenic photosynthesis during Precambrian times entailed the diversification of strategies minimizing reactive oxygen species-associated damage.
Claudia Alvarez-Carreño +2 more
doaj +1 more source
BMEMat, EarlyView.This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang +11 more
wiley +1 more source