Results 61 to 70 of about 13,066 (196)

Preleukemia: hematological disorders prior to onset of leukemia [PDF]

open access: yes, 1975
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi   +5 more
core   +1 more source

White Blood Cell Enumeration and Differential by Flow Cytometry: The ICSH WBC Reference Method

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 1, Page 93-101, February 2026.
ABSTRACT Introduction The current reference method for the white blood cell (WBC) differential is manual smear review as outlined in CLSI H20‐A2. As with many manual methods, it suffers from a number of challenges including dependence upon the expertise of the interpreter, the quality of the smear and stain, when dysplastic features make cell ...
Benjamin D. Hedley   +6 more
wiley   +1 more source

Off-Pump Coronary Revascularization Using Bilateral Internal Thoracic Arteries in A Patient with Paroxysmal Nocturnal Hemoglobinuria: A Case Report

open access: yesBrazilian Journal of Cardiovascular Surgery
Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra-orphan disease. We report the first case in the literature of Off-Pump Coronary Revascularization Using Bilateral Internal Thoracic Arteries in a patient with paroxysmal nocturnal hemoglobinuria. A 36-
Juan Mariano Vrancic   +3 more
doaj   +1 more source

Microconfined flow behavior of red blood cells by image analysis techniques [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +4 more
core  

Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells [PDF]

open access: yes, 2014
Latently HIV-1-infected cells are recognized as the last barrier toward viral eradication and cure. To purge these cells, we combined a provirus stimulant with a blocker of human CD59, a key member of the regulators of complement activation, to trigger ...
Amet, Tohti   +10 more
core   +2 more sources

PAROXYSMAL HEMOGLOBINURIA [PDF]

open access: yesJournal of the American Medical Association, 1914
History. —J., a man aged 45, Swedish, a sheet-metal worker, entered the Peter Bent Brigham Hospital, Sept. 11, 1913, complaining of chills, fever and bloody urine. The family history was unimportant as related to the present illness. The patient had interstitial keratitis at 3 years (?), and measles and small-pox as a child, but no other infectious ...
openaire   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

open access: yesHaematologica, 2010
Background Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively controlled with eculizumab.
Anita Hill   +6 more
doaj   +1 more source

Paroxysmal nocturnal hemoglobinuria: Pandora’s box?

open access: yesJournal of Mind and Medical Sciences, 2020
Introduction. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired non-malignant hematological disorder which affects the pluripotent hematopoietic stem cell.
Mihnea-Alexandru Găman   +2 more
doaj   +1 more source

Heme induces endothelial tissue factor expression: Potential role in hemostatic activation in patients with hemolytic anemia [PDF]

open access: yes, 2008
Objectives: We explored the possibility that heme, an inflammatory mediator and a product of intravascular hemolysis in patients with hemolytic anemia including sickle cell disease, could modulate hemostasis by an effect on endothelial tissue factor (TF)
Betal, Suhita G.   +3 more
core   +2 more sources

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