Results 91 to 100 of about 20,766 (204)

A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]

open access: yes, 2019
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J   +17 more
core   +2 more sources

Short-term recurrent coronary artery thrombosis with acute myocardial infarction in a patient with aplastic anemia–paroxysmal nocturnal hemoglobinuria syndrome: a case report

open access: yesFrontiers in Cardiovascular Medicine
BackgroundAcute myocardial infarction commonly occurs in patients with coronary artery disease, but rarely, it can develop under a hypercoagulable state.
Xue-Guo Fu   +3 more
doaj   +1 more source

Thrombolytic therapy is effective in paroxysmal nocturnal hemoglobinuria: a series of nine patients and a review of the literature

open access: yesHaematologica, 2012
Background Thrombosis is the major risk factor for death in patients with paroxysmal nocturnal hemoglobinuria. Previous case reports indicate that venous thrombosis in patients with paroxysmal nocturnal hemoglobinuria is amenable to thrombolysis.Design ...
David J. Araten   +14 more
doaj   +1 more source

Methemoglobinemia without hemolytic anemia following exposure to naphthalene moth balls

open access: yesJournal of Pediatric Critical Care, 2019
Mothballs are commonly used household product that contain an aromatic hydrocarbon named naphthalene. On systemic exposure it causes oxidant injury to hemoglobin molecules resulting in oxidized forms of hemoglobin like methaemoglobin and further ...
Snehamayee Nayak   +3 more
doaj   +1 more source

Paroxysmal Nocturnal Hemoglobinuria: Diagnostic Challenges in Pediatric Patient

open access: yesCase Reports in Pediatrics, 2019
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening hematologic stem cell disorder characterized by hemoglobinuria, thrombosis, and tendency for bone marrow failure.
Dharshana Krishnaprasadh   +3 more
doaj   +1 more source

Polymorphism of the complement receptor 1 gene correlates with the hematologic response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

open access: yesHaematologica, 2014
Complement blockade by eculizumab is clinically effective in hemolytic paroxysmal nocturnal hemoglobinuria. However, the response is variable and some patients remain dependent on red blood cell transfusions.
Tommaso Rondelli   +14 more
doaj   +1 more source

Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]

open access: yes, 2018
Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
core   +1 more source

Application of a policy framework for the public funding of drugs for rare diseases [PDF]

open access: yes, 2014
BACKGROUND: In many countries, decisions about the public funding of drugs are preferentially based on the results of randomized trials. For truly rare diseases, such trials are not typically available, and approaches by public payers are highly variable.
Christine Seager   +10 more
core   +1 more source

Thrombotic Thrombocytopenic Purpura, Moschcowitz Syndrome [PDF]

open access: yes, 2001
The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was ...
Czinyéri, Judit   +4 more
core  

Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria. [PDF]

open access: yes, 2016
Background. Host responses to infection are critical determinants of disease severity and clinical outcome. The development of tools to risk stratify children with malaria is needed to identify children most likely to benefit from targeted interventions.
Barker, Kevin R.   +10 more
core   +1 more source

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