First milestone of this Ph.D. thesis was the successful extension of conventional NTA/His-tag technique to self-assembling, multivalent chelator thiols for high-affinity recognition as well as stable and uniform immobilization of His-tagged proteins on ...
Tinazli, Ali
core
Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
Protein engineering could be used to bring two proteins together, which don't normally interact, in an oriented configuration. Using computer modelling and experimental work involving mutagenesis, a new dimer complex, (α7)2, was engineered with two α ...
Mantri, Shiksha
core +1 more source
Proteomic investigation of the group B streptococcus
The Group B Streptococcus (GBS) is a Gram-positive opportunistic pathogen which is a leading cause of neonatal disease globally. In 2000-2001, the general incidence of neonatal GBS infection was 0.72 per 1000 live births in U.K. and the mortality rate is
Yang, Qian
core
The toxic effects of α-hemolysin and β-hemolysin produced by <i>Staphylococcus aureus</i>. [PDF]
Zhang Q, Wu Y, Luo D, Fang F.
europepmc +1 more source
Genetic and Phenotypic Characteristics of Five <i>Staphylococcus aureus</i> Strains Isolated from Yakutian Cattle. [PDF]
Fursova K +15 more
europepmc +1 more source
Der katalytische Zyklus der Nukleotid-bindenden Domäne des ABC-Transporters HlyB
Nucleotide-binding domains (NBDs), roughly 27 kDa in size, are conservative components of the large family of ABC (ATP-binding cassette) transporters, which includes importers, exporters, and receptors.
Zaitseva, Jelena
core
Production of a Renibacterium salmoninarum hemolysin fusion protein in Escherichia coli K12 [PDF]
TH Grayson +3 more
openaire +1 more source
An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain. [PDF]
Korotkov VS +9 more
europepmc +1 more source
Pangenomics-Driven Reverse Vaccinology for the Discovery of New Vaccine Candidates Against <i>Bordetella pertussis</i>. [PDF]
Abdelouahab M, Idrissa D.
europepmc +1 more source
Arresting the Activity of Bacterial β-Barrel Pore-Forming Toxins by Cysteine Insertion Mutagenesis in the Homologous Region. [PDF]
Siunov AV +9 more
europepmc +1 more source

