Results 51 to 60 of about 6,457,465 (175)

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

open access: yesGut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei   +5 more
wiley   +1 more source

A Novel Oxidized Low-Density Lipoprotein-Binding Protein, Asp-Hemolysin, Recognizes Lysophosphatidylcholine.

open access: yesBiological and Pharmaceutical Bulletin, 2002
Oxidized low-density lipoprotein (Ox-LDL) plays an important role in the initiation and progression of atherosclerosis. Asp-hemolysin, a hemolytic toxin from Aspergillus fumigatus, is a specific, high affinity binding protein for Ox-LDL. We have previously shown that Ox-LDL strongly inhibits the hemolytic activity of Asp-hemolysin, and that the removal
Yoichi, Kudo   +5 more
openaire   +3 more sources

Study of SarA by DNA Affinity Capture Assay (DACA) Employing Three Promoters of Key Virulence and Resistance Genes in Methicillin-Resistant Staphylococcus aureus

open access: yesAntibiotics, 2022
Methicillin-resistant Staphylococcus aureus (MRSA), one of the most well-known human pathogens, houses many virulence factors and regulatory proteins that confer resistance to diverse antibiotics.
Byungchan Kim   +10 more
doaj   +1 more source

Oral proton‐reprogrammed nanomedicine to break the inflammatory bowel disease‐Clostridium difficile infection vicious cycle

open access: yesiMeta, EarlyView.
Research on the mechanism of OPR restoring intestinal epithelial cell (IEC) structure and function in inflammatory bowel disease (IBD) treatment. (A) Schematic diagram of OPR structure and the rate of GP release under different conditions. (B) Schematic diagram of OPR targeting IBD colonic lesions through charge interaction.
Wensheng Chen   +7 more
wiley   +1 more source

Myricetin protects Galleria mellonella against Staphylococcus aureus infection and inhibits multiple virulence factors

open access: yesScientific Reports, 2017
Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options.
L. N. Silva   +6 more
doaj   +1 more source

Comparative proteomic analysis of Streptococcus suis biofilms and planktonic cells that identified biofilm infection-related immunogenic proteins. [PDF]

open access: yesPLoS ONE, 2012
Streptococcus suis (SS) is a zoonotic pathogen that causes severe disease symptoms in pigs and humans. Biofilms of SS bind to extracellular matrix proteins in both endothelial and epithelial cells and cause persistent infections.
Yang Wang   +7 more
doaj   +1 more source

Bacterial delivery of Staphylococcus aureus α-hemolysin causes regression and necrosis in murine tumors.

open access: yesMolecular Therapy, 2014
Bacterial therapies, designed to manufacture therapeutic proteins directly within tumors, could eliminate cancers that are resistant to other therapies.
Adam T St Jean   +4 more
semanticscholar   +1 more source

Green Synthesis of ZnO Nanoparticles From Spirulina platensis: Antimicrobial and Cytotoxic Evaluation With Molecular Docking Studies

open access: yesChemistryOpen, EarlyView.
Algal‐extract‐derived ZnO nanoparticles show shape anisotropy and are bio capped by phytochemicals. These green‐synthesized NPs strongly inhibit S. aureus and K. pneumoniae biofilms. Molecular docking suggests stable binding of surface biomolecules to microbial targets, highlighting synergistic antibacterial mechanisms.
Muhammad Rizwan   +8 more
wiley   +1 more source

Solvent‐Mediated Dewetting Principles for Cell‐Sized Liposome Formation

open access: yesSmall, EarlyView.
Dynamics of solvent‐mediated dewetting for giant unilamellar liposome formation. Solvent removal, through changing lipid packing and membrane tension, is shown to induce partial dewetting into equilibrium low and high budding angle morphologies. Complete dewetting requires mechanical force, quantified using optical tweezers.
Mostafa Bakouei   +6 more
wiley   +1 more source

Insights into the Genome Sequence of Chromobacterium amazonense Isolated from a Tropical Freshwater Lake

open access: yesInternational Journal of Genomics, 2018
Members of the genus Chromobacterium have been isolated from geographically diverse ecosystems and exhibit considerable metabolic flexibility, as well as biotechnological and pathogenic properties in some species.
Alexandre Bueno Santos   +8 more
doaj   +1 more source

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