Results 41 to 50 of about 20,967 (222)

First Case of Staphylococci Carrying Linezolid Resistance Genes from Laryngological Infections in Poland

open access: yesPathogens, 2021
Linezolid is currently used to treat infections caused by multidrug-resistant Gram-positive cocci. Both linezolid-resistant S. aureus (LRSA) and coagulase-negative staphylococci (CoNS) strains have been collected worldwide.
Michał Michalik   +5 more
doaj   +1 more source

A simple method to make, trap and deform a vesicle in a gel

open access: yesScientific Reports, 2023
We present a simple method to produce giant lipid pseudo-vesicles (vesicles with an oily cap on the top), trapped in an agarose gel. The method can be implemented using only a regular micropipette and relies on the formation of a water/oil/water double ...
Pierre Tapie   +4 more
doaj   +1 more source

Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins.

open access: yesPLoS ONE, 2014
Staphylococcus aureus is a major human pathogen that elaborates several exotoxins. Among these are the bicomponent leukotoxins (BCLs), which include γ-hemolysin, Panton-Valentine leukocidin (PVL), and LukDE.
Machi Yanai   +6 more
doaj   +1 more source

A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings

open access: yesMicromachines, 2020
Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano   +6 more
doaj   +1 more source

Leptospiral TlyC is an extracellular matrix‐binding protein and does not present hemolysin activity [PDF]

open access: yesFEBS Letters, 2009
The role of TlyA, TlyB and TlyC proteins in the biology of Leptospira is still uncertain. Although these proteins have been considered as putative hemolysins, we demonstrate that leptospiral recombinant TlyB and TlyC do not possess hemolytic activity.
Carvalho, Eneas   +12 more
openaire   +3 more sources

SINGLE-MOLECULE DETECTION AND MANIPULATION WITH BIOLOGICAL NANOPORES

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2021
Single-molecule electrophysiology techniques using protein-based or solid-state nanopores as nanoreactors were proven incredibly useful as platforms for sensing and biophysical characterisation of biological molecules (e.g., peptides, proteins), DNA ...
Irina SCHIOPU   +5 more
doaj   +1 more source

THE PROTEIN ASSOCIATED WITH HEMOLYSIN IN RABBIT SERUM AND PLASMA [PDF]

open access: yesJournal of General Physiology, 1927
1. The water-insoluble globulin with which hemolysin is associated, may be separated from immune serum or plasma by dilution and simple dialysis at optimal pH. 2. This optimum in plasma is influenced by the presence of the fibrinogen. 3.
openaire   +2 more sources

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

open access: yesAngewandte Chemie, EarlyView.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng   +3 more
wiley   +2 more sources

Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice

open access: yesBMC Cancer, 2005
Background Serine-threonine kinases of the Raf family (A-Raf, B-Raf, C-Raf) are central players in cellular signal transduction, and thus often causally involved in the development of cancer when mutated or over-expressed.
Troppmair Jakob   +6 more
doaj   +1 more source

Crystal Structure of Hcp from Acinetobacter baumannii: A Component of the Type VI Secretion System. [PDF]

open access: yesPLoS ONE, 2015
The type VI secretion system (T6SS) is a bacterial macromolecular machine widely distributed in Gram-negative bacteria, which transports effector proteins into eukaryotic host cells or other bacteria.
Federico M Ruiz   +5 more
doaj   +1 more source

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