Results 51 to 60 of about 6,571,241 (229)
Electrostatic Control of Polymer Translocation Speed through α-Hemolysin Protein Pore [PDF]
Macromolecules, 2016 The electrostatic origins behind the speed of translocation of a uniformly charged flexible macromolecule through α-hemolysin (αHL) protein pores under a voltage are investigated using variations in pH and electrolyte concentration. We have measured durations of successful threading of poly(styrenesulfonate) through αHL at two different pH conditions ...
Byoung-Jin, Jeon, Murugappan, Muthukumar
openaire +2 more sources
Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
Antibiotics, 2022 Methicillin-resistant Staphylococcus aureus (MRSA), one of the most well-known human pathogens, houses many virulence factors and regulatory proteins that confer resistance to diverse antibiotics.
Byungchan Kim +10 more
doaj +1 more source
Animal Research and One Health, EarlyView.Supplementation with mannan oligosaccharides (MOS) enhances growth, disease resistance, antioxidant capacity, and gut microbiota diversity while suppressing inflammation, apoptosis, and strengthening intestinal barrier integrity in zebrafish challenged with LPS or DSS.
Zhiyuan Lu +4 more
wiley +1 more source
Scientific Reports, 2017 Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options.
L. N. Silva +6 more
doaj +1 more source
Comparative proteomic analysis of Streptococcus suis biofilms and planktonic cells that identified biofilm infection-related immunogenic proteins. [PDF]
PLoS ONE, 2012 Streptococcus suis (SS) is a zoonotic pathogen that causes severe disease symptoms in pigs and humans. Biofilms of SS bind to extracellular matrix proteins in both endothelial and epithelial cells and cause persistent infections.
Yang Wang +7 more
doaj +1 more source
Journal of Biological Chemistry, 2014 Background: Group B Streptococcus (GBS) activates the NLRP3 inflammasome. Results: GBS RNA escapes the phagolysosome and activates the NLRP3 inflammasome in a β-hemolysin-dependent fashion.
Rahul Gupta +18 more
semanticscholar +1 more source
Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology
Exploration, EarlyView.Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen +8 more
wiley +1 more source
Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines [PDF]
Inflammation, 1992 A striking similarity exists between the pathogenetic properties of group A streptococci and those of activated mammalian professional phagocytes (neutrophils, macrophages). Both types of cells are endowed by the ability to adhere to target cells; to elaborate oxidants, hydrolases, and membrane-active agents (hemolysins, phospholipases); and to freely ...
Varani, James +5 more
openaire +3 more sources
Molecular Therapy, 2014 Bacterial therapies, designed to manufacture therapeutic proteins directly within tumors, could eliminate cancers that are resistant to other therapies.
Adam T St Jean +4 more
semanticscholar +1 more source