Single-Molecule Study of Proteins by Biological Nanopore Sensors
Nanopore technology has been developed for detecting properties of proteins through monitoring of ionic current modulations as protein passes via a nanosize pore.
Dongmei Wu +3 more
doaj +1 more source
Synthesized Geopolymers Adsorb Bacterial Proteins, Toxins, and Cells
Pore-forming and hemolytic toxins are bacterial cytotoxic proteins required for virulence in many pathogens, including staphylococci and streptococci, and are notably associated with clinical manifestations of disease.
John Popovich +10 more
doaj +1 more source
Electrostatic Control of Polymer Translocation Speed through α-Hemolysin Protein Pore [PDF]
The electrostatic origins behind the speed of translocation of a uniformly charged flexible macromolecule through α-hemolysin (αHL) protein pores under a voltage are investigated using variations in pH and electrolyte concentration. We have measured durations of successful threading of poly(styrenesulfonate) through αHL at two different pH conditions ...
Byoung-Jin, Jeon, Murugappan, Muthukumar
openaire +2 more sources
Platelets, Bacterial Adhesins and the Pneumococcus
Systemic infections with pathogenic or facultative pathogenic bacteria are associated with activation and aggregation of platelets leading to thrombocytopenia and activation of the clotting system.
Kristin Jahn +4 more
doaj +1 more source
Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Schirrmacher, V. +7 more
core +1 more source
Bee venom (BV) is a rich source of secondary metabolites from honeybees (Apis mellifera L.). It contains a variety of bioactive ingredients including peptides, proteins, enzymes, and volatile metabolites. This study investigated the antibacterial effects
Kabakci Dilek +2 more
doaj +1 more source
Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines [PDF]
A striking similarity exists between the pathogenetic properties of group A streptococci and those of activated mammalian professional phagocytes (neutrophils, macrophages). Both types of cells are endowed by the ability to adhere to target cells; to elaborate oxidants, hydrolases, and membrane-active agents (hemolysins, phospholipases); and to freely ...
Varani, James +5 more
openaire +3 more sources
Expression, purification and hemolytic activity of rL-hemolysin proteins.
(A). Hemolysin genes amplified from genomic DNA of L. interrogans strain Lai. Lane AM: DNA marker (Fermentas, Canada). Lane A1: blank control. Lanes A2 to A9: amplicons of the sph1 (1674 bp), sph2 (1869 bp), sph3 (1557 bp), sph4 (717 bp), hlpA (939 bp ...
Yifei Wu (313108) +7 more
core +1 more source
In-Depth Analysis of Exoproteomes from Marine Bacteria by Shotgun Liquid Chromatography-Tandem Mass Spectrometry: the Ruegeria pomeroyi DSS-3 Case-Study [PDF]
Microorganisms secrete into their extracellular environment numerous compounds that are required for their survival. Many of these compounds could be of great interest for biotechnology applications and their genes used in synthetic biology design.
Joseph Alexander Christie-Oleza +3 more
core +1 more source
We evaluated the genetic diversity of Streptococcus suis isolates of different serotypes by macrorestriction analysis and elucidated possible relationships between the genetic background, expression of potential virulence traits, and source of isolation.
Smith, H.E. +9 more
core +1 more source

