Results 61 to 70 of about 1,567,080 (217)

Insights into the Genome Sequence of Chromobacterium amazonense Isolated from a Tropical Freshwater Lake

open access: yesInternational Journal of Genomics, 2018
Members of the genus Chromobacterium have been isolated from geographically diverse ecosystems and exhibit considerable metabolic flexibility, as well as biotechnological and pathogenic properties in some species.
Alexandre Bueno Santos   +8 more
doaj   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

open access: yesMedicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du   +10 more
wiley   +1 more source

Myricetin protects Galleria mellonella against Staphylococcus aureus infection and inhibits multiple virulence factors

open access: yesScientific Reports, 2017
Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options.
L. N. Silva   +6 more
doaj   +1 more source

Associated roles of hemolysin and p60 protein for the intracellular growth ofBacillus subtilis [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 2006
Hemolysin expressing Bacillus subtilis strain (B. subtilis ble/hlA) was used as a carrier for listerial protein p60 to study the impact of this protein on bacterial virulence independent of other gene products of Listeria monocytogenes. Bacillus subtilis ble/hlyA exhibited longer cell chains than B. subtilis ble/hlyA/iap.
Jarosław, Wiśniewski   +2 more
openaire   +2 more sources

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

open access: yesSmall, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale   +10 more
wiley   +1 more source

How We Simulate Nanopores

open access: yesSmall Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz   +5 more
wiley   +1 more source

Bacillus cereus Decreases NHE and CLO Exotoxin Synthesis to Maintain Appropriate Proteome Dynamics During Growth at Low Temperature

open access: yesToxins, 2020
Cellular proteomes and exoproteomes are dynamic, allowing pathogens to respond to environmental conditions to sustain growth and virulence. Bacillus cereus is an important food-borne pathogen causing intoxication via emetic toxin and/or multiple protein ...
Catherine Duport   +3 more
doaj   +1 more source

TolC, an Escherichia coli outer membrane protein required for hemolysin secretion. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1990
Secretion of Escherichia coli alpha-hemolysin into the medium does not require the cleavage of an N-terminal signal peptide. The specific secretion apparatus was shown to consist of two proteins, HlyB and HlyD, both located in the inner membrane and encoded by genes contiguous to the hemolysin structural gene (hlyA).
C, Wandersman, P, Delepelaire
openaire   +2 more sources

Peptide Fingerprinting of Single Protein Molecules Using In‐Plane Nanopore Sensors Integrated to an Extended Immobilized Nanoscale Enzymatic Reactor (eINER)

open access: yesSmall Methods, EarlyView.
The protein Time‐of‐Flight (P‐ToF) chip can peptide fingerprint a single protein molecule by subjecting it to a solid phase endopeptidase cleavage reaction in‐line with a combination of resistive pulse sensing of the resulting single peptides and machine‐learning aided identification.
Suresh Shivanka   +7 more
wiley   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

open access: yesInsect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo   +2 more
wiley   +1 more source

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