Results 71 to 80 of about 6,390 (173)

Potential role of hemopexin in venous thromboembolism (VTE) mediated through effects on apoptosis-related proteins

Hematology
Objective: The limited understanding of venous thromboembolism (VTE) has hindered the development of novel treatment approaches. This study aimed to identify critical factors underlying VTE.Methods: The isobaric tags for relative and absolute ...
Jun-li Zhuang, Xiao-hui Yu, Hua-gang Liu, Peng Tang, Hong-ping Deng, Jie Li, Jiang-qiao Zhou, Zhong-jun Zhang   +7 more
doaj   +1 more source

Is Hemopexin a Nephrotoxin or a Marker of Kidney Injury in Renal Ischemia-Reperfusion?

Biomolecules
Destabilization of heme proteins is recognized to play a role in acute kidney injury (AKI). Hemopexin (Hpx), known for its role in binding heme, mitigates free heme toxicity. Despite this, the potential adverse effects of Hpx deposition in kidney tissues
You Hyun Jeon, Eun-Joo Oh, Se-Hyun Oh, Jeong-Hoon Lim, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim   +9 more
doaj   +1 more source

Proteomic Characterization of the Heart and Skeletal Muscle Reveals Widespread Arginine ADP-Ribosylation by the ARTC1 Ectoenzyme

Cell Reports, 2018
Summary: The clostridium-like ecto-ADP-ribosyltransferase ARTC1 is expressed in a highly restricted manner in skeletal muscle and heart tissue. Although ARTC1 is well studied, the identification of ARTC1 targets in vivo and subsequent characterization of
Mario Leutert, Stephan Menzel, Rickmer Braren, Björn Rissiek, Ann-Katrin Hopp, Kathrin Nowak, Lavinia Bisceglie, Peter Gehrig, Hui Li, Anna Zolkiewska, Friedrich Koch-Nolte, Michael O. Hottiger   +11 more
doaj   +1 more source

Targeting heme in sickle cell disease: new perspectives on priapism treatment

Frontiers in Physiology
Men with sickle cell disease (SCD) frequently experience priapism, defined as prolonged, painful erections occurring without sexual arousal or desire. This urological emergency can lead to penile fibrosis and permanent erectile dysfunction if not treated
Tammyris Helena Rebecchi Silveira, Fabiano Beraldi Calmasini, Mariana Gonçalves de Oliveira, Fernando Ferreira Costa, Fábio Henrique Silva   +4 more
doaj   +1 more source

Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury

Frontiers in Immunology
IntroductionPulmonary ischemia-reperfusion (IR) injury (IRI) plays a significant role in various lung disorders and is a key factor in the development of primary graft dysfunction following lung transplantation.
Tomoyuki Nakagiri, Tomoyuki Nakagiri, Nadine R. Köhler, Sabina Janciauskiene, Sabina Janciauskiene, Sabina Janciauskiene, Lavinia Neubert, Lavinia Neubert, Ann-Kathrin Knöfel, Ann-Kathrin Knöfel, Pooja Pradhan, Arjang Ruhparwar, Fabio Ius, Fabio Ius, Stephan Immenschuh   +14 more
doaj   +1 more source

Human Hemopexin

Journal of Biological Chemistry, 1974
Philip Aisen, Adela Leibman, Daniel C. Harris, Thomas Moss   +3 more
openaire   +1 more source

Hemopexin [PDF]

, 2020
openaire   +1 more source

Is hemolysis a novel therapeutic target in COVID-19?

Frontiers in Immunology, 2022
Daiki Ousaka, Masahiro Nishibori
doaj   +1 more source

Hemopexin (HPX) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Integrating Single-Cell Profiling with Generative AI for <i>De Novo</i> Design of MMP9 Protein Binders in Diffuse Large B-Cell Lymphoma. [PDF]

Molecules
Miao Z, Zhu S, Qin L, Ma D, Lai M, Xu P, Jin Y, Cai H, Zhao S, Wang Y.   +9 more
europepmc   +1 more source