Results 1 to 10 of about 16,295 (220)

Identification and epidemiology of a novel Hepacivirus in domestic ducks in Hunan province, China [PDF]

Frontiers in Veterinary Science
The genus Hepacivirus comprises a diverse range of genetically distinct viruses that infect both mammalian and non-mammalian hosts, with some posing significant risks to human and animal health.
Jin-Tao Chen, Kang-Jing Chen, Kang-Wei Wu, Shan-Hong Yi, Jian-Wei Shao   +4 more
doaj   +8 more sources

An Equine Model for Vaccination against a Hepacivirus: Insights into Host Responses to E2 Recombinant Protein Vaccination and Subsequent Equine Hepacivirus Inoculation [PDF]

Viruses, 2022
Equine hepacivirus (EqHV) is the closest known genetic homologue of hepatitis C virus. An effective prophylactic vaccine is currently not available for either of these hepaciviruses. The equine as potential surrogate model for hepacivirus vaccine studies
Marcha Badenhorst, Armin Saalmüller, Janet M. Daly, Reinhard Ertl, Maria Stadler, Christina Puff, Madeleine de le Roi, Wolfgang Baumgärtner, Michael Engelmann, Sabine Brandner, Hannah K. Junge, Barbara Pratscher, Asisa Volz, Bertrand Saunier, Thomas Krey, Johannes Wittmann, Steffen Heelemann, Julien Delarocque, Bettina Wagner, Daniel Todt, Eike Steinmann, Jessika-M. V. Cavalleri   +21 more
doaj   +7 more sources

A Novel Hepacivirus in Wild Rodents from South America [PDF]

Viruses, 2019
The Hepacivirus genus comprises single-stranded positive-sense RNA viruses within the family Flaviviridae. Several hepaciviruses have been identified in different mammals, including multiple rodent species in Africa, Asia, Europe, and North America.
William Marciel de Souza, Marcílio Jorge Fumagalli, Gilberto Sabino-Santos, Felipe Gonçalves Motta Maia, Sejal Modha, Márcio Roberto Teixeira Nunes, Pablo Ramiro Murcia, Luiz Tadeu Moraes Figueiredo   +7 more
doaj   +9 more sources

The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China [PDF]

BioMed Research International, 2018
Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of
Deng, Yu, Guan, Su Hua, Hao, Guiying, Rasmussen, Thomas Bruun, Wang, Silu   +4 more
core   +8 more sources

Identification of a Novel Hepacivirus in Southeast Asian Shrew (Crocidura fuliginosa) from Yunnan Province, China [PDF]

Pathogens, 2023
The genus Hepacivirus contains single-stranded positive-sense RNA viruses belonging to the family Flaviviridae, which comprises 14 species. These 14 hepaciviruses have been found in different mammals, such as primates, dogs, bats, and rodents.
Ling Guo, Bei Li, Peiyu Han, Na Dong, Yan Zhu, Fuli Li, Haorui Si, Zhengli Shi, Bo Wang, Xinglou Yang, Yunzhi Zhang   +10 more
doaj   +4 more sources

Description of an Equine Hepacivirus Cluster in a Horse Stable in Italy [PDF]

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Equine hepacivirus (EqHV), also known as Hepacivirus A, represents the most closely related genetic homologue of human hepatitis C virus (HCV). Although detected worldwide, limited information on the clinical features of this infection is available and on the mechanisms by which EqHV is transmitted.
Roberta Cardone, Alessio Buonavoglia, Gianvito Lanave, Violetta Iris Vasinioti, Valentina Mininni, Eleonora Lorusso, Nicola Decaro, Vito Martella, Gabriella Elia, Georgia Diakoudi   +9 more
wiley   +4 more sources

CD4+ T cell help during early acute hepacivirus infection is critical for viral clearance and the generation of a liver-homing CD103+CD49a+ effector CD8+ T cell subset. [PDF]

PLoS Pathogens
In hepatitis C virus (HCV) infection, CD4+ and CD8+ T cells are crucial for viral control. However, a detailed understanding of the kinetic of CD4+ T cell help and its role in the generation of different CD8+ T cell subsets during acute infection is ...
Jarrett Lopez-Scarim, Dustyn Mendoza, Shashank M Nambiar, Eva Billerbeck   +3 more
doaj   +3 more sources

First National Prevalence in Italian Horse Population and Phylogenesis Highlight a Fourth Sub-Type Candidate of Equine Hepacivirus. [PDF]

Viruses
equine hepacivirus (EqHV, Flaviviridae, hepacivirus) is a small, enveloped RNA virus generally causing sub-clinical hepatitis with occasional fatalities. EqHV is reported in equids worldwide, but for Italy data are limited.
Nardini R, Pacchiarotti G, Svicher V, Salpini R, Bellocchi MC, Conti R, Sala MG, La Rocca D, Carioti L, Cersini A, Manna G, The Equine Hepatic Viruses Consortium, Scicluna MT.   +12 more
europepmc   +5 more sources

Hepatic iNKT cells produce type 2 cytokines and restrain antiviral T cells during acute hepacivirus infection [PDF]

Frontiers in Immunology, 2022
Chronic hepatitis C virus (HCV) infection is a curable disease, but the absence of a vaccine remains a major problem in infection prevention. The lack of small animal models and limited access to human liver tissue impede the study of hepatic antiviral ...
Svjetlana Raus, Jarrett Lopez-Scarim, Joshua Luthy, Eva Billerbeck   +3 more
doaj   +2 more sources

Viruses in Horses with Neurologic and Respiratory Diseases [PDF]

Viruses, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan, Yanpeng Li, Gilberto Sabino-Santos Jr, Vorthon Sawaswong, Samantha Barnum, Nicola Pusterla, Xutao Deng, Eric Delwart   +7 more
doaj   +3 more sources