Ecologic Traits Analysis for Identifying Rodent Hosts for Arenavirus and Hepacivirus in the Americas [PDF]
More than half of the emerging or re‐emerging pathogens that affect human health have their origin in wildlife. Among these rodents are key zoonotic hosts due to their unique characteristics of life history and species diversity.
María del Carmen Villalobos‐Segura +3 more
semanticscholar +3 more sources
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice
Background & Aims Human genetic variation is thought to guide the outcome of hepatitis C virus (HCV) infection but model systems within which to dissect these host genetic mechanisms are limited.
Ariane J. Brown +21 more
openalex +2 more sources
Detection of Equine Parvovirus-Hepatitis Virus and Equine Hepacivirus in Archived Sera from Horses in France and Australia [PDF]
Reports of newly discovered equine hepatotropic flavi- and parvoviruses have emerged throughout the last decade in many countries, the discovery of which has stimulated a great deal of interest and clinical research.
Christine Fortier +12 more
openalex +2 more sources
First National Prevalence in Italian Horse Population and Phylogenesis Highlight a Fourth Sub-Type Candidate of Equine Hepacivirus [PDF]
Equine hepacivirus (EqHV, Flaviviridae, hepacivirus) is a small, enveloped RNA virus generally causing sub-clinical hepatitis with occasional fatalities. EqHV is reported in equids worldwide, but for Italy data are limited.
Roberto Nardini +11 more
openalex +2 more sources
Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection [PDF]
An effective vaccine for the hepatitis C virus (HCV) remains an unmet medical need. There is no animal model for assessing HCV vaccines; however, rodent hepacivirus (RHV) infection in laboratory rats recapitulates the lifelong chronic hepatotropic ...
Sheetal Trivedi +13 more
doaj +2 more sources
Equine hepacivirus: phylogenetic analysis of Italian horse sequences highlights a fourth subtype candidate [PDF]
openalex +2 more sources
Horses and other equids can be infected with several viruses of the family Flaviviridae, belonging to the genus Flavivirus and Hepacivirus. This consensus statement focuses on viruses with known occurrence in Europe, with the objective to summarize the ...
Jessika‐M. V. Cavalleri +6 more
doaj +1 more source
Dose-Dependent Hepacivirus Infection Reveals Linkage between Infectious Dose and Immune Response
More than 70 million people worldwide are still infected with the hepatitis C virus 30 years after its discovery, underscoring the need for a vaccine. To develop an effective prophylactic vaccine, detailed knowledge of the correlates of protection and an
André Gömer +9 more
doaj +1 more source
Equine hepacivirus and equine parvovirus‐hepatitis in hospitalised horses in Austria [PDF]
openalex +2 more sources

