Results 51 to 60 of about 20,741 (247)
Non-primate hepacivirus infection with apparent hepatitis in a horse — Short communication [PDF]
Non-primate hepacivirus (NPHV) is a recently identified hepacivirus (family Flaviviridae) in dog and horse; however, the disease associations remain unknown.
Boros, Ákos+3 more
core +1 more source
Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV
Lack of tractable immunocompetent animal models amenable to robust experimental challenge impedes vaccine efforts for HCV. Infection with rodent hepacivirus from Rattus norvegicus (RHV‐rn1) in rats shares HCV‐defining characteristics, including liver ...
Raphael Wolfisberg+12 more
semanticscholar +1 more source
Design principles and applications of synthetic self‐replicating RNAs
Self‐replicating RNAs (srRNAs) replicate enzymatically in the cytosol. Depending on their bespoke gene cargo, srRNAs can be transformed into powerful tools for various applications. Abstract With the advent of ever more sophisticated methods for the in vitro synthesis and the in vivo delivery of RNAs, synthetic mRNAs have gained substantial interest ...
Alexander Wagner, Hannes Mutschler
wiley +1 more source
The genetics of immune and infection phenotypes in wild mice, Mus musculus domesticus
Abstract Wild animals are under constant threat from a wide range of micro‐ and macroparasites in their environment. Animals make immune responses against parasites, and these are important in affecting the dynamics of parasite populations. Individual animals vary in their anti‐parasite immune responses.
Louise Cheynel+3 more
wiley +1 more source
Simple Summary This is a comprehensive review containing the most up-to-date information on Equine Hepacivirus, one of the recently discovered hepatic equine viruses, together with an analysis of serological and biomolecular presence presented in ...
Giulia Pacchiarotti+2 more
semanticscholar +1 more source
Epidemiology of hepatitis C in Croatia in the European context [PDF]
We analyzed prevalence, risk factors and hepatitis C virus (HCV) genotype distribution in different population groups in Croatia in the context of HCV epidemiology in Europe, with the aim to gather all existing information on HCV infection in Croatia ...
Barbić, Ljubo+7 more
core +1 more source
Animal models to study hepatitis C virus infection [PDF]
With more than 71 million chronically infected people, the hepatitis C virus (HCV) is a major global health concern. Although new direct acting antivirals have significantly improved the rate of HCV cure, high therapy cost, potential emergence of drug ...
Ahmed Atef Mesalam+4 more
core +3 more sources
Further Evidence for in Utero Transmission of Equine Hepacivirus to Foals [PDF]
(1) Background: Equine hepacivirus (EqHV), also referred to as non-primate hepacivirus (NPHV), infects horses—and dogs in some instances—and is closely related to hepatitis C virus (HCV) that has infected up to 3% of the world’s human population, causing an epidemic of liver cirrhosis and cancer.
Pronost, Stéphane+8 more
openaire +5 more sources
Identification of a pegivirus (GBV-like virus) that infects horses [PDF]
The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB virus-like viruses) in these species.
Brock, Kenny V+10 more
core +1 more source
Comparison of different in situ hybridization techniques for the detection of various RNA and DNA viruses [PDF]
In situ hybridization (ISH) is a technique to determine potential correlations between viruses and lesions. The aim of the study was to compare ISH techniques for the detection of various viruses in different tissues.
Baechlein, C. (Christine)+14 more
core +2 more sources