Results 51 to 60 of about 41,094 (191)

Therapy of acute hepatitis C infection [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj   +1 more source

Characterization of nonprimate hepacivirus and construction of a functional molecular clone [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance The origin of hepatitis C virus (HCV) has long remained a mystery. Unexpectedly, a plethora of HCV-related hepaciviruses was recently discovered in horses, monkeys, rodents, and bats. These discoveries are of particular interest and may aid in understanding HCV evolution, molecular biology, and natural history.
Troels K. H. Scheel   +14 more
openaire   +3 more sources

Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer

open access: yesViruses, 2020
Members of Picornaviridae and of the Hepacivirus, Pegivirus and Pestivirus genera of Flaviviridae all contain an internal ribosomal entry site (IRES) in the 5′-untranslated region (5′UTR) of their genomes. Each class of IRES has a conserved structure and
Yani Arhab   +3 more
doaj   +1 more source

Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice [PDF]

open access: green, 2023
Ariane J. Brown   +20 more
openalex   +2 more sources

Identification of a Novel Hepacivirus in Domestic Cattle from Germany [PDF]

open access: yesJournal of Virology, 2015
ABSTRACT Hepatitis C virus (HCV) continues to represent one of the most significant threats to human health. In recent years, HCV-related sequences have been found in bats, rodents, horses, and dogs, indicating a widespread distribution of hepaciviruses among animals. By applying unbiased high-throughput sequencing, a novel virus
Christine, Baechlein   +11 more
openaire   +2 more sources

Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam

open access: yesViruses, 2018
Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins,
Dung Van Nguyen   +10 more
doaj   +1 more source

Viruses in Horses with Neurologic and Respiratory Diseases

open access: yesViruses, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan   +7 more
doaj   +1 more source

Collaborative Referral Model to Achieve Hepatitis C Micro-Elimination in Methadone Maintenance Treatment Patients during the COVID-19 Pandemic

open access: yesViruses, 2022
Although hepatitis C virus (HCV) prevails in patients receiving methadone maintenance treatment (MMT), most do not receive anti-HCV therapy. This single-center observational study aimed to achieve HCV micro-elimination at an MMT center during the COVID ...
Chi-Ming Tai   +13 more
doaj   +1 more source

Canine hepacivirus is not associated with chronic liver disease in dogs [PDF]

open access: yesJournal of Viral Hepatitis, 2013
SummaryCanine hepacivirus (CHV) has recently been identified in liver and respiratory tract samples from dogs, and comparative phylogenetic analysis has confirmed it to be the closest genetic relative of hepatitis C virus (HCV) described to date. CHV offers great potential as a model system for HCV, but only if the underlying processes of infection and
Bexfield, N. H.   +4 more
openaire   +2 more sources

Evolution and Diversity of Hepatitis C Virus and Peculiarity of Modern Laboratory Diagnostic of Hepatitis C Markers

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Hepatitis C virus (HCV), which was identified in 1989 - 1990. Later it was included in new genus Hepacivirus of the family Flaviviridae. Due the genetic heterogeneity of HCV, viral isolates was decided to classificate on genotypes and sybtypes in ...
L. I. Nikolaeva   +2 more
doaj   +1 more source

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