Results 51 to 60 of about 41,094 (191)
Therapy of acute hepatitis C infection [PDF]
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj +1 more source
Characterization of nonprimate hepacivirus and construction of a functional molecular clone [PDF]
Significance The origin of hepatitis C virus (HCV) has long remained a mystery. Unexpectedly, a plethora of HCV-related hepaciviruses was recently discovered in horses, monkeys, rodents, and bats. These discoveries are of particular interest and may aid in understanding HCV evolution, molecular biology, and natural history.
Troels K. H. Scheel +14 more
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Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer
Members of Picornaviridae and of the Hepacivirus, Pegivirus and Pestivirus genera of Flaviviridae all contain an internal ribosomal entry site (IRES) in the 5′-untranslated region (5′UTR) of their genomes. Each class of IRES has a conserved structure and
Yani Arhab +3 more
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Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice [PDF]
Ariane J. Brown +20 more
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Identification of a Novel Hepacivirus in Domestic Cattle from Germany [PDF]
ABSTRACT Hepatitis C virus (HCV) continues to represent one of the most significant threats to human health. In recent years, HCV-related sequences have been found in bats, rodents, horses, and dogs, indicating a widespread distribution of hepaciviruses among animals. By applying unbiased high-throughput sequencing, a novel virus
Christine, Baechlein +11 more
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Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins,
Dung Van Nguyen +10 more
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Viruses in Horses with Neurologic and Respiratory Diseases
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan +7 more
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Although hepatitis C virus (HCV) prevails in patients receiving methadone maintenance treatment (MMT), most do not receive anti-HCV therapy. This single-center observational study aimed to achieve HCV micro-elimination at an MMT center during the COVID ...
Chi-Ming Tai +13 more
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Canine hepacivirus is not associated with chronic liver disease in dogs [PDF]
SummaryCanine hepacivirus (CHV) has recently been identified in liver and respiratory tract samples from dogs, and comparative phylogenetic analysis has confirmed it to be the closest genetic relative of hepatitis C virus (HCV) described to date. CHV offers great potential as a model system for HCV, but only if the underlying processes of infection and
Bexfield, N. H. +4 more
openaire +2 more sources
Hepatitis C virus (HCV), which was identified in 1989 - 1990. Later it was included in new genus Hepacivirus of the family Flaviviridae. Due the genetic heterogeneity of HCV, viral isolates was decided to classificate on genotypes and sybtypes in ...
L. I. Nikolaeva +2 more
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