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Binding of Rat Thyroglobulin to Heparan Sulfate Proteoglycans
Thyroid, 2000We previously showed that rat thyroglobulin (Tg) is a heparin-binding protein and that heparin inhibits Tg binding to megalin (gp330), an endocytic Tg receptor found on the apical surface of thyrocytes. Cooperation between cell surface receptors and heparin-like molecules, namely heparan sulfate proteoglycans (HSPGs), can facilitate cell surface ...
MARINO', MICHELE +2 more
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Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans
Glycobiology, 2001Heparanases are endoglycosidases that cleave the heparan sulfate glycosaminoglycans from proteoglycan core proteins and degrade them to small oligosaccharides. Inside cells, these enzymes are important for the normal catabolism of heparan sulfate proteoglycans (HSPGs), generating glycosaminoglycan fragments that are then transported to lysosomes and ...
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Heparan sulfate proteoglycans in invasion and metastasis
Seminars in Cell & Developmental Biology, 2001Because heparan sulfate proteoglycans mediate cell adhesion and control the activities of numerous growth and motility factors, they play a critical role in regulating the metastatic behavior of tumor cells. Due to their utilitarian nature, heparan sulfate proteoglycans may at times act as inhibitors of cell invasion and at other times as promoters of ...
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Autoantibodies to heparan sulfate proteoglycans
Autoimmunity Reviews, 2002Yves, Renaudineau +4 more
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BIOLOGICAL SIGNIFICANCE OF HEPARAN SULFATE PROTEOGLYCANS*
Annals of the New York Academy of Sciences, 1982V, Buonassisi, P, Colburn
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Heparan Sulfate Proteoglycans in Central Synapses
2014Yu Yamaguchi, Fumitoshi Irie
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Neurofibrillary tangles contain heparan sulfate proteoglycans
Neurobiology of Aging, 1990openaire +1 more source