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Structure and Function of the Heparan Sulfate Proteoglycans [PDF]
Heparan sulfate proteoglycans are a complex and heterogeneous family of macromolecules. They are composed of linear sulfated polysaccharide chains, the heparan sulfate moieties, that are covalently attached to protein. Their distribution is nearly ubiquitous.
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Autoantibodies to heparan sulfate proteoglycans
Autoimmunity Reviews, 2002Maryvonne Dueymes +4 more
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Heparan Sulfate Proteoglycans in Cancer Therapy
2011The polyanionic linear polysaccharide heparan sulfate specifically interacts with a multitude of extracellular ligands relevant to all steps of tumor progression. Heparan sulfate proteoglycans act as coreceptors for cytokine and chemokine signaling, modulating tumor cell growth and survival, chemotaxis, and angiogenesis.
Martin Götte +2 more
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BIOLOGICAL SIGNIFICANCE OF HEPARAN SULFATE PROTEOGLYCANS*
Annals of the New York Academy of Sciences, 1982P. Colburn, V. Buonassisi
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Heparan Sulfate Proteoglycans in Central Synapses [PDF]
Yu Yamaguchi, Fumitoshi Irie
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