Results 171 to 180 of about 102,406 (252)

Ex Vivo Effect of Apixaban on Hemostatic Biomarkers in Children With Heart Disease: A SAXOPHONE Trial Substudy. [PDF]

open access: yesJ Am Heart Assoc
Aborkhees GA   +14 more
europepmc   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

open access: yesArtificial Organs, EarlyView.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci   +9 more
wiley   +1 more source

International Delphi consensus on feminising genital surgery in assigned‐male‐at‐birth individuals

open access: yesBJU International, EarlyView.
Objective To achieve an international expert consensus among surgeons on the indications, contraindications, and perioperative management of feminising genital surgery (FGS) for assigned‐male‐at‐birth (AMAB) individuals, using a Delphi process. Methods A two‐round on‐line Delphi survey (May–July 2025) followed by a final consensus meeting (September ...
Marta Pezzoli   +30 more
wiley   +1 more source

Synthetic biology for heparin biomanufacturing. [PDF]

open access: yesBioresour Bioprocess
Pan Y   +15 more
europepmc   +1 more source

Intermittent cocaine use patterns, not total intake, predict cue‐induced drug seeking in rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cocaine‐associated cues trigger relapse to drug use in humans and animal models. In rats, long daily cocaine access (4–6 vs. 1–2 h) increases drug self‐administration and cue‐induced cocaine seeking, suggesting that greater intake promotes relapse.
Amélie Mainville‐Berthiaume   +6 more
wiley   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys   +14 more
wiley   +1 more source

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell-Selective Bioactivity. [PDF]

open access: yesMacromol Biosci
Cosimi A   +9 more
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock   +9 more
wiley   +1 more source

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