Results 191 to 200 of about 188,098 (289)

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

Artificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly, Diane Tobolt, Bat‐Erdene Namsrai, Benjamin Fisher, Anthony An‐Fa Dahm Chen, Joseph Sushil Rao, Srivasupradha Ramesh, Anudari Chimedtseren, Mark Clemens, Charles Y. Lee, John C. Bischof, Erik B. Finger   +11 more
wiley   +1 more source

Immediate Pulmonary Embolism or Pulmonary Artery Thrombosis Following Blunt Chest Injury? [PDF]

Eur J Case Rep Intern Med
Siddiqui T, Muhammad K, El-Menyar A, Atique S, Ahmed K, Rizoli S, Al-Thani H.   +6 more
europepmc   +1 more source

Pediatric Versus Adult Shear‐Induced Hemolysis—Are Age‐Related Blood Properties the Main Cause for Differences?

Artificial Organs, EarlyView.
Graphical summary of the experimental comparison of shear‐induced hemolysis in pediatric and adult blood using a Couette shearing device. Pediatric blood shows a trend toward lower increase in hemolysis at higher shear stress amplitudes, while no relevant differences are observed at low and intermediate stresses.
Vera Froese, Meike Fahrenholz, Ulrich Kertzscher, Michael Lommel, Maren Kleine‐Brueggeney   +4 more
wiley   +1 more source

Low-Molecular-Weight Sulfated Chitosan Microparticles Efficiently Bind HIV-1 In Vitro: Potential for Microbicide Applications. [PDF]

Molecules
Bucarey SA, Ramos V, Hidalgo AA, Neira V, Neira-Carrillo A, Ferrer P.   +5 more
europepmc   +1 more source

Evaluation of a Rat Cardiopulmonary Bypass Model Using an Extraluminal Flow Oxygenator

Artificial Organs, EarlyView.
A rat cardiopulmonary bypass model was constructed incorporating the developed extraluminal flow oxygenator and compared with a commercial intraluminal flow oxygenator. Both oxygenators demonstrated comparable gas exchange performance and inflammatory responses; however, the one developed in this study better preserved PLT counts.
Hirohito Sumikura, Yutaka Fujii, Shunsuke Uchiyama, Akihiko Homma   +3 more
wiley   +1 more source

Comparing Heparin and Heparin Mimetics in Targeting Immunomodulatory Proteins from Platelets to Activate T Cell-Dependent Immune Response in Oncology. [PDF]

ACS Pharmacol Transl Sci
Nekipelov K, Otto S, Henseler M, Vidal-Y-Sy S, Al Nahain A, Gorzelanny C, Ferro V, Bendas G.   +7 more
europepmc   +1 more source

Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion

Artificial Organs, EarlyView.
Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer, Magdalena Kött, Andras T. Meszaros, Michael J. Blumer, Bettina Zelger, Stefan Redl, Martin Hermann, Thomas Resch, Simon Mathis, Gabriel Putzer, Judith Martini, Christina Bogensperger, Franka Messner, Julia Hofmann, Margot Fodor, Andrea Griesmacher, Annemarie Weissenbacher, Theresa Hautz, Gert Mayer, Hannes Neuwirt, Gerald Brandacher, Silvia Oberparleiter, Stefan Schneeberger   +22 more
wiley   +1 more source

Efficacy and safety of pharmacological and procedural interventions in the management of hypertriglyceridemia-induced acute pancreatitis: a systematic review. [PDF]

Saudi Pharm J
Al-Ismail M, Promi T, Hetai R, Ahmed S, Awaisu A.   +4 more
europepmc   +1 more source

Predictors of Brain Infarction in Pediatric Patients During Extracorporeal Membrane Oxygenation

Artificial Organs, EarlyView.
In 179 pediatric ECMO patients, brain infarction (BI) occurred in 28% and was linked to markedly higher 30‐day mortality. VA ECMO mode (vs. VV) and higher pre‐ECMO arterial lactate independently predicted BI, supporting standardized neuro‐monitoring and liberal early brain CT, especially for children on VA ECMO.
Riccardo Iacobelli, Thomas Fux, Sara Wood Schalling, Sarah Kopfer, Jonas Berner, Alexander Fletcher‐Sandersjöö, Lars Mikael Broman   +6 more
wiley   +1 more source

Weight-adjusted low molecular weight heparin with surgery morning dose administration: Impact on hip hemiarthroplasty early infections. [PDF]

World J Orthop
Nageeb Mahmoud AM, Maniar HH, Bernate J, Horwitz DS.   +3 more
europepmc   +1 more source